Lu Group Publications 2024
425 | Yunling Deng, Jing-Xiang Wang, Barshali Ghosh, and Yi Lu
"Enzymatic CO2 Reduction Catalyzed by Natural and Artificial Metalloenzymes"
J. Inorg. Biochem. 259, 112669,(2024) [doi]
424 | David Moreira, Daniela Alexandre, André Miranda, Pedro Lourenço, Pedro V. Baptista, Cândida Tomaz, Yi Lu, Carla Cruz
"Detecting mir-155-3p through a molecular beacon bead-based assay"
Molecules 29(13), 3182 (2024) [doi]
422 | Ruocan Qian, Man-sha Wu, Zheng-lin Yang, Yuting Wu, Wei-jie Guo, Ze-rui Zhou, Xiao-yuan Wang, Da-wei Li, and Yi Lu
"Rectifying artificial nanochannels with multiple interconvertible permeability states"
Nature Comm. 15, 2051 (2024) [doi]
421 | Huanhuan Fan and Yi Lu
"Improving Sensitivity of a Mn(II)-Specific DNAzyme for Cellular Imaging Sensor through Sequence Mutations,"
Anal. Chem. 96, 9, 3853–3858 (2024) [doi]
420 | Yu Zhou, Shuaizhen Zhou, Scott Lyons, Haoran Sun, Jonathan V. Sweedler, and Yi Lu
"Enhancing 2-Pyrone Synthase Efficiency by High-Throughput Mass-Spectrometric Quantification and In Vitro/In Vivo Catalytic Performance Correlation"
ChemBioChem, 25, e202300849 (2024) [doi]
419 | Daniel J. Cooke, Esther Y. Maier, Dr. Tyler L. King, Haoding Lin, Santiago Hendrichs, Slade Lee, Dr. Noushaba N. Mafy, Kathleen M. Scott, Yi Lu, Emily L. Que
"Dual Nanoparticle Conjugates for Highly Sensitive and Versatile Sensing Using 19F Magnetic Resonance Imaging"
Angew. Chem. Int. Ed. 63, e202312322 (2024) [doi]
418 | Ruo-Can Qian, Yuting Wu, Zhenglin Yang, Weijie Guo, Ze-Rui Zhou and Yi Lu
"Metal-Dependent DNAzymes for Cell Surface Engineering and Intracellular Bioimaging"
DNA Nanotechnology for Cell Research: From Bioanalysis to Biomedicine” Zhou Nie ed. Wiley P143-168 (2024)
417 | Yuan Ma, Weijie Guo, Quanbing Mou, Xiangli Shao, Mingkuan Lyu, Valeria Garcia, Linggen Kong, Whitney Lewis, Carson Ward, Zhenglin Yang, Xingxin Pan, S. Stephen Yi, Yi Lu
"Spatial imaging of glycoRNA in single cells with ARPLA"
Nature Biotechnol 42, 608–616 (2024) [doi]
2023
416 | Jing-Xiang Wang, Avery C. Vilbert, Chang Cui, Evan N. Mirts, Lucas H. Williams, Wantae Kim, Y. Jessie Zhang and Yi Lu
"Increasing Reduction Potentials of Type 1 Copper Center and Catalytic Efficiency of Small Laccase from Streptomyces coelicolor through Secondary Coordination Sphere Mutations"
Angew. Chem. Int. Ed. e202314019 (2023) [doi]
415 | Yiwei Liu, Kevin A. Harnden, Casey Van Stappen, Sergei A. Dikanov, and Yi Lu
"A designed Histidine-brace enzyme for oxidative depolymerization of polysaccharides as a model of lytic polysaccharide monooxygenase"
Proc Natl Acad Sci. USA, 120, 43, e2308286120 (2023) [doi]
414 | Casey Van Stappen, Huiguang Dai, Anex Jose, Shiliang Tian, Edward I. Solomon, and Yi Lu
"Primary and Secondary Coordination Sphere Effects on the Structure and Function of S-nitrosylating Azurin"
J. Am. Chem. Soc. 145, 37, 20610–20623 (2023) [doi]
413 | Mengyi Xiong, Yuting Wu, Gezhi Kong, Whitney Lewis, Zhenglin Yang, Hanxiao Zhang, Li Xu, Ying Liu, Qin Liu, Xuhua Zhao, Xiao-Bing Zhang and Yi Lu
"A Semisynthetic Bioluminescence Sensor for Ratiometric Imaging of Metal Ions In Vivo Using DNAzymes Conjugated to an Engineered Nano-Luciferase"
Angew. Chem. Int. Ed. 62, e202308086 (2023) [doi]
412 | Yuting Wu, Whitney Lewis, Jing Luen Wai, Mengyi Xiong, Jiao Zheng, Zhenglin Yang, Chloe Gordon, Ying Lu, Siu Yee New, Xiao-Bing Zhang and Yi Lu
"Ratiometric Detection of Zn2+ Using DNAzyme-Based Bioluminescence Resonance Energy Transfer Sensors"
,” Chemistry 5 (Special Issue on Functional Biomolecule-Based Composites and Nanostructures: Current Developments and Applications—A Themed Issue in Honor of Prof. Dr. Itamar Willner), 1745–1759 (2023) [doi]
411 | Amir H. Ahkamia, Odeta Qafokua, Tiina Roose, Quanbing Mou, Yi Lu, Zoe G. Cardon, Yuxin Wu, Chunwei Chou, Joshua B. Fisher, Tamas Varga, Pubudu Handakumbura, Jayde A. Aufrecht, Arunim Bhattacharjee, and James J. Moran
"Emerging Sensing, Imaging, and Computational Technologies to Unravel Nano- to Macroscale Rhizosphere Dynamics – Review and Research Perspectives"
Soil Biol. & Biochem. 109253, (2023) [doi]
410 | Kenneth N. McGuinness, Nolan Fehon, Ryan Feehan, Michelle Miller, Andrew C. Mutter, Justin Nam, Jenna E. AbuSalim, Joshua T. Atkinson, Hirbod Heidari, Natalie Losada, J. Dongun Kim, Ronald L. Koder, Yi Lu, Jonathan J. Silberg, Joanna S.G. Slusky, Paul G. Falkowski, Vikas Nanda
"Surveying protein-cofactor energetics to understand deep-time oxidoreductase evolution"
PROTEINS: Struct. Funct. Bioinform 92, 52-29 (2023) [doi]
409 | Yiwei Liu, Nicholas M. Marshall, Shengsong Yu, Wantae Kim, Yi-Gui Gao, Howard Robinson, Mark J. Nilges, Yan Zhang, Siu Yee New, Yi Lu
"Structural basis for the effects of phenylalanine on tuning the reduction potential of type 1 copper in azurin"
Inorg. Chem. 62, 11618–11625 (2023) [doi]
408 | Zhimei Huang, Xianbo Ma, Fengze Jiang, Rong Wang, Zhenkun Wu, and Yi Lu
"Dual Spatially Localized DNA Walker for Fast and Efficient RNA Detection"
Nano Lett. 23, 6042–6049 (2023) [doi]
407 | Huanhuan Fan, Claire E. McGhee, Ryan J. Lake, Zhenglin Yang, Zijian Guo, Xiao-Bing Zhang, and Yi Lu
"A Highly Selective Mn(II)-Specific DNAzyme and Its Application in Intracellular Sensing"
JACS Au 3, 6, 1615–1622 (2023) [doi]
406 | Yuting Wu, Seyed-Fakhreddin Torabi, Ryan J. Lake, Shanni Hong, Zhengxin Yu, Peiwen Wu, Zhenglin Yang, Kevin Nelson, Weijie Guo, Gregory T. Pawel, Jacqueline Van Stappen, Xiangli Shao, Liviu M. Mirica, and Yi Lu
"Simultaneous Fe(II)/Fe(III) imaging shows Fe(III) over Fe(II) enrichment in Alzheimer’s disease mouse brain"
Science Adv. 9 (2023) [doi]
405 | Yunling Deng, Sudharsan Dwaraknath, Wenhao O. Ouyang, Cory J. Matsumoto, Stephanie Ouchida, and Yi Lu
"Engineering an Oxygen-Binding Protein for Photocatalytic CO2 Reductions in Water"
Angew Chemie Int. Ed. e202215719 (2023) [doi]
404 | Xiaojing Wang, Skye Shepherd, Nantao Li, Congnyu Che, Tingjie Song, Yanyu Xiong, Isabella Rose Palm, Bin Zhao, Manish Kohli, Utkan Demirci, Yi Lu, Brian Cunningham
"A Target Recycling Amplification Process for the Digital Detection of Exosomal MicroRNAs through Photonic Resonator Absorption Microscopy"
Angew Chemie Int. Ed. e202217932 (2023) [doi]
403 | Yu Zhou, Dr. Evan N. Mirts, Sangdo Yook, Dr. Matthew Waugh, Rachel Martini, Yong-Su Jin, Yi Lu
"Reshaping the 2-Pyrone Synthase Active Site for Chemoselective Biosynthesis of Polyketides"
Angew Chemie Int. Ed. 62, e2022124 (2023) [doi]
402 | Shanni Hong, Zhenglin Yang, Quanbing Mou, Yunxia Luan, Bingbo Zhang, Renjun Pei and Yi Lu
"Monitoring leaching of Cd2+ from cadmium-based quantum dots by an Cd aptamer fluorescence sensor"
Biosensors & Bioelectronics 220, 114880 (2023) [doi]
401 | Aaron P. Ledray, Sudharsan Dwaraknath, Khetpakorn Chakarawet, Madeline R. Sponholtz, Claire Merchen, Casey Van Stappen, Guodong Rao, R. David Britt, Yi Lu
"Tryptophan Can Promote Oxygen Reduction to Water in a Biosynthetic Model of Heme Copper Oxidases"
Biochemistry 62, 2, 388–395 (2023) [doi]
2022
400 | Ruo-Can Qian, Ze-Rui Zhou, Yuting Wu, Zhenglin Yang, Weijie Guo, Da-Wei Li, Yi Lu
"Combination Cancer Treatment: Using Engineered DNAzyme Molecular Machines for Dynamic Inter- and Intracellular Regulation"
Angew Chemie Int. Ed. (2022) 61, e2022109 [doi]
399 | Tingjie Song, Xiaojing Wang, Dongbao Yao, Haojun Liang, and Yi Lu
"Identifying and Differentiating Topological G-Quadruplex Structures with DNA-encoded Plasmonic Gold Nanoparticles"
Angew Chemie Int. Ed. 61, e202204201 (2022) [doi]
398 | Gregory T. Pawel, Yuan Ma, Yuting Wu, Yi Lu and Ana Sol Peinetti
"Binding Affinity Measurements Between DNA Aptamers and their Virus Targets Using ELONA and MST"
Bio-protocol 12(21): e4548 (DOI:[10.21769/BioProtoc.4548]) (2022)
397 | Casey Van Stappen, Yunling Deng, Yiwei Liu, Hirbod Heidari, Jing-Xiang Wang, Yu Zhou, Aaron P. Ledray, Yi Lu
"Designing Artificial Metalloenzymes by Tuning of the Environment beyond the Primary Coordination Sphere"
Chem. Rev. 122, 14, 11974–12045 (2022)[doi]
396 | Marcos Ezequiel Gramajo1, Ryan J. Lake, Yi Lu and Ana Sol Peinetti
"In vitro Selection of Aptamers to Differentiate Infectious from Non-infectious Viruses"
J. Visual. Exp. https://dx.doi.org/10.3791/64127(2022)
395 | Quanbing Mou, Xueyi Xue, Yuan Ma, Mandira Banik, Valeria Garcia, Weijie Guo, Jiang Wang, Tingjie Song, Li-Qing Chen, and Yi Lu
"Efficient delivery of a DNA aptamer-based biosensor into plant cells for glucose sensing through thiol-mediated uptake "
Science Advances 8 (2022) [doi]
394 |Yang Yu, Nicholas M. Marshall, Dewain K. Garner, Mark J. Nilges, Yi Lu
"Tuning reduction potentials of type 1 copper center in azurin by replacing a histidine ligand with its isostructural analogues"
J. Inorg. Biochem (Special Issue in Memory of Richard H. Holm), 234, 11863 (2022)[doi]
393 | Xiaojing Wang, Gun Kim, James L. Chu, Tingjie Song, Zhenglin Yang, Weijie Guo, Xiangli Shao,Michael L. Oelze, King C. Li and Yi Lu
"Noninvasive and Spatiotemporal Control of DNAzyme-Based Imaging of Metal Ions In Vivo Using High-Intensity Focused Ultrasound"
J. Am. Chem. Soc. 144, 5812–5819 (2022)[doi]
392 | JingJing Zhang, Tian Lan, and Yi Lu
"Overcoming Major Barriers to Developing Successful Sensors for Practical Applications Using Functional Nucleic Acids"
Annu. Rev. Anal. Chem. 15, 151-171 (2022)[doi]
391 | Nantao Li, Xiaojing Wang, Joseph Tibbs, Congnyu Che, Ana S. Peinetti, Bin Zhao, Leyang Liu, Priyash Barya, Laura Cooper, Lijun Rong, Xing Wang, Yi Lu and Brian T. Cunningham
"Label-Free Digital Detection of Intact Virions by Enhanced Scattering Microscopy"
J. Am. Chem. Soc. 2022, 144, 4, 1498–1502 (2022) [doi]
390 | Yiming Wang, Nitya sai Reddy Satyavolu, Hong Yang, Yi Lu
"Kinetic Reconstruction of DNA-Programed Plasmonic Metal Nanostructures with Predictable Shapes and Optical Properties"
J. Am. Chem. Soc. 144, 10, 4410–4421 (2022)[doi]
2021
389 | Claire E. McGhee, Zhenglin Yang, Weijie Guo, Yuting Wu, Mingkuan Lyu, Cynthia J. DeLong, Shanni Hong, Yuan Ma, Melvin G. McInnis, K. Sue O’Shea, and Yi Lu
"DNAzyme-Based Lithium-Selective Imaging Reveals Higher Lithium Accumulation in Bipolar Disorder Patient-Derived Neurons"
ACS Cent. Sci. 7, 1809–1820 (2021) [PDF] [doi][news]
388 | Yansha Gao, Songbai Zhang, Chengwei Wu, Qian Li, Zhifa Shen,Yi Lu, Zai-Sheng Wu
"Self-Protected DNAzyme Walker with a Circular Bulging DNA Shield for Amplified Imaging of miRNAs in Living Cells and Mice"
ACS Nano 15, 19211–19224 (2021) [PDF] [doi]
387 | Nantao Li, Bin Zhao, Robert Stavins, Ana Sol Peinetti, Neha Chauhan, Rashid Bashir, Brian T. Cunningham, William P. King, Yi Lu Enrique Valera, Xing Wang
"Overcoming the limitations of COVID-19 diagnostics with nanostructures, nucleic acid engineering, and additive manufacturing"
Cur. Opin. Solid State & Material Science, 26, 100966 (2021)[PDF] [doi]
386 | Ana S. Peinetti, Ryan J. Lake, Wen Cong, Laura Cooper, Yuting Wu, Yuan Ma, Gregory T. Pawel, María Eugenia Toimil-Molares, Christina Trautmann, Lijun Rong, Benito Mariñas, Omar Azzaroni, and Yi Lu
"Direct detection of human adenovirus or SARS-CoV-2 with ability to inform infectivity using DNA aptamer-nanopore sensors"
Sci. Adv. 7, eabh2848 (2021) [PDF] [doi][news]
385 | Yuan Ma, Quanbing Mou, Peng Yan, Zhenglin Yang, Ying Xiong, Deyue Yan, Chuan Zhang, Xinyuan Zhu and Yi Lu
"A highly sensitive and selective fluoride sensor based on a riboswitch-regulated transcription coupled with CRISPR-Cas13a tandem reaction"
Chem. Sci. 12, 11740-11747(2021) [PDF] [doi]
384 | Lu Yu, Aokun Liu, Bingbo Zhang, Jian Kuang, Xiaoqi Guo, Changlin Tian and Yi Lu
"Dipolar Coupling-Based Electron Paramagnetic Resonance Method for Protease Enzymatic Characterization and Inhibitor Screening"
Chem. Commun. 57, 9602-9605 (2021) [PDF] [doi]
383 | Jiao Zheng, Jing Luen Wai, Ryan J. Lake, Siu Yee New, Zhike He, and Yi Lu
"DNAzyme Sensor Uses Chemiluminescence Resonance Energy Transfer for Rapid, Portable, and Ratiometric Detection of Metal Ions"
Anal. Chem. 93, 31, 10834–10840 (2021) [PDF] [doi]
382 | Mingkuan Lyu, Linggen Kong, Zhenglin Yang, Yuting Wu, Claire E. McGhee, and Yi Lu
"PNA-Assisted DNAzymes to Cleave Double-Stranded DNA for Genetic Engineering with High Sequence Fidelity"
J. Am. Chem. Soc. 143, 9724–9728 (2021) [PDF] [doi] [news]
381 | Erin M. McConnell, Ioana Cozmaa, Quanbing Mou, John D. Brennan, Yi Lu and Yingfu Li
"Biosensing with DNAzymes"
Chem Soc. Rev. 50, 8954-8994 (2021) [doi]
378 | Shanni Hong, Gregory T. Pawel, Renjun Pei and Yi Lu
"Recent progress in developing fluorescent probes for imaging cell metabolites"
Biomed. Mater. 16, 044108 (2021) [PDF] [doi]
377 | Shiliang Tian, Ruixi Fan, Therese Albert, Rahul L. Khade, Huiguang Dai, Kevin A. Harnden, Parisa Hosseinzadeh, Jing Liu, Mark J. Nilges, Yong Zhang, Pierre Moënne-Loccoz, Yisong Guo, and Yi Lu
"Stepwise Nitrosylation of the Nonheme Iron Site in an Engineered Azurin and a Molecular Basis for Nitric Oxide Signaling Mediated by Nonheme Iron Proteins"
Chem. Sci. 12, 6569-6579 (2021) [PDF] [doi]
376 | Kevin A. Harnden, Yajie Wang, Lam Vo, Huimin Zhao, and Yi Lu
"Engineering Artificial Metalloenzymes"
In “Protein Engineering: Tools and Applications,” Huimin Zhao, ed. pp177-206 (2021)
375 | Lawrence Que, Jr. and Yi Lu
"Bio-Coordination Chemistry: An Introduction"
Section 8 (Biocoordination Chemistry) Lawrence Que, Jr. and Yi Lu, eds., Comprehensive Coordination Chemistry III, Edwin Constable Gerard Parkin Lawrence Que, eds., pp 1-2 (2021)
374 | Matthew W. Waugh, Sudharsan Dwaraknath and Yi Lu
"Advances in Metalloprotein Design and Engineering: Strategies Employed and Insights Gained"
In Section 8 (Biocoordination Chemistry) Lawrence Que, Jr. and Yi Lu, eds., Comprehensive Coordination Chemistry III, Edwin Constable Gerard Parkin Lawrence Que, eds. pp 900-928 (2021)
373 | Ruo-Can Qian, Ze-Rui Zhou, Weijie Guo, Yuting Wu, Zhenglin Yang, and Yi Lu
"Cell Surface Engineering using DNAzymes: Metal Ion-mediated Control of Cell-Cell Interactions"
J. Am. Chem. Soc. 143, 5737–5744 (2021) [PDF] [doi]
372 | Shige Xing, Yao Lin, Liangyuan Cai, Prem N. Basa, Austin K. Shigemoto, Chengbin Zheng, Feng Zhang, Shawn C. Burdette and Yi Lu
"Detection and Quantification of Tightly-Bound Zn2+ in Blood Serum Using a Photocaged Chelator and a DNAzyme Fluorescent Sensor"
Anal. Chem. 93, 5856–5861 (2021)
371 | Wentao Xu, Wanchong He, Zaihui Du, Liye Zhu, Kunlun Huang, Yi Lu, Yunbo Luo
"Functional Nucleic Acid-Nanomaterials: Development, Properties, and Applications"
Angew Chemie Int. Ed. 60, 6890-6918 (2021) [PDF] [doi]
370 | Songbai Zhang, Yunxia Luan, Mengyi Xiong, Jingjing Zhang, Ryan Lake, and Yi Lu
"DNAzyme amplified aptasensing platform for ochratoxin A detection using personal glucose meter"
ACS Appl. Mater. Interfaces (Special theme issue on Materials Applications of Aptamers) 13, 9472–9481 (2021) [PDF] [doi]
369 | Igor D. Petrik, Roman Davydov, Maximilian Kahle, Braddock Sandoval, Sudharsan Dwaraknath, Pia Adelroth, Brian Hoffman, Yi Lu
"An Engineered Glutamate in Biosynthetic Models of Heme-Copper Oxidases Drives Complete Product Selectivity by Tuning the Hydrogen-Bonding Network"
Biochemistry 60, 346–355 (2021) [PDF] [doi]
368 | Christopher J. Reed, Quan N. Lam, Evan N. Mirts and Yi Lu
"Molecular understanding of heteronuclear active sites in heme–copper oxidases, nitric oxide reductases, and sulfite reductases through biomimetic modelling"
Chem. Soc. Rev. 50, 2486-2539 (2021) [PDF] [doi]
2020
367 | Yiming Wang, Michael J. Counihan, Jeffrey Wayjer Lin, Joaquín Rodríguez-López, Hong Yang, and Yi Lu
"Quantitative Analysis of DNA-Mediated Formation of Metal Nanocrystals"
J. Am. Chem. Soc. 142, 48, 20368–20379 (2020) [PDF] [doi]
366 | Evan N. Mirts, Sergei A. Dikanov, Anex Jose, Edward I. Solomon, and Yi Lu
"A Binuclear CuA Center Designed in an All α-Helical Protein Scaffold"
J. Am. Chem. Soc. 142, 32, 13779–13794 (2020) [PDF] [doi]
365 | Sheng-Song Yu, Jun-Jie Li, Chang Cui, Shiliang Tian, Jie-Jie Chen, Han-Qing Yu, Changjun Hou, Mark J. Nilges, and Yi Lu
"Structural Basis for the Quadratic Relationship between Electronic Absorption and Electronic Paramagnetic Resonance Parameters of Type 1 Copper Proteins"
Inorg. Chem. 59, 10620–10627 (2020) [PDF] [doi]
364 | Chang Xue, Songbai Zhang, Xin Yu, Shuyao Hu, Yi Lu, and Zai-Sheng Wu
"Periodically-Ordered Nick-Hidden DNA Nanowire with Cell-Specific Aptamer Targeting Ligands as Highly Serum-Stable and Selective Theranostic Agents"
Angew Chemie Int. Ed. 59, 17540–17547 (2020) [PDF] [doi]
363 | Yuting Wu, Zhenglin Yang and Yi Lu
"Photocaged functional nucleic acids for spatiotemporal imaging in biology"
Curr. Opin. Chem. Biol. 57, 95-104 (2020) [PDF] [doi]
362 | Changhe Ouyang, Songbai Zhang, Chang Xue, Xin Yu, Huo Xu, Zhenmeng Wang, Yi Lu, Zai-Sheng Wu
"Precision-Guided Missile-Like DNA Nanostructure Containing Warhead and Guidance Control for Aptamer-Based Targeted Drug Delivery into Cancer Cells in Vitro and in Vivo"
J. Am. Chem. Soc. 142, 1265-1277 (2020) [PDF] [doi]
361 | Yugang Bai, Hang Xing, Yunhao Bai, Li Huey Tan, Kevin Hwang, Ji Li, Yi Lu, Steven C. Zimmerman
"Independent Control over Size, Valence, and Elemental Composition in the Synthesis of DNA-Nanoparticle Conjugates"
Chem. Sci. 11, 1564-1572 (2020) [PDF] [doi]
360 | Ying Xiong, Jingjing Zhang, Zhenglin Yang, Quanbing Mou, Yuan Ma, Yonghua Xiong, Yi Lu
"DNA Regulated CRISPR-Cas12a Sensors for Point-of-Care Diagnostics of Non-Nucleic Acid Targets"
J. Am. Chem. Soc. 142, 207-213 (2020) [PDF] [doi]
359 | JingJing Zhang, Tian Lan, Yi Lu
"Translating in vitro Diagnostics from Centralized Laboratories to Point-of-Cares using Commercially-Available Handheld Meters"
Trac-Trends Anal. Chem. 124, 115782 (2020) [doi]
358 | Samantha G. Zambuto, Julio F. Serrano, Avery C. Vilbert, Yi Lu, Brendan Harley, Sara Pedron
"Response of neuroglia to hypoxia-induced oxidative stress using enzymatically crosslinked hydrogels"
MRS Communications 10, 83-90 (2020) [doi]
357 | Ana Sol Peinetti, Ryan Lake, Yi Lu
"Functional DNA Sensors for Heavy Metal Ions and Microbial Contaminants in Water"
In Water Sensors (Junhong Chen and Matthew Tirrell eds.), World Scientific Publishing Company (in press) (2020)
356 | Shanni Hong, Xiaoting Zhang, Ryan J. Lake, Gregory T. Pawel, Zijian Guo, Renjun Pei and Yi Lu
"A photo-regulated aptamer sensor for spatiotemporally controlled monitoring of ATP in mitochondria of living cells"
Chem. Sci. 11, 713-720 (2020) [PDF] [doi] [news]
355 | Mengyi Xiong, Zhenglin Yang, Ryan J. Lake, Junjie Li, Shanni Hong, Huanhuan Fan, Xiao-Bing Zhang, Yi Lu
"DNAzyme-Mediated Genetically Encoded Sensors for Ratiometric Imaging of Metal Ions in Living Cells"
Angew. Chemie Int. Ed. 132, 1907-1912 (2020) [PDF] [doi]
2019
354 | Chang Xue, Songbai Zhang, Congcong Li, Xin Yu, Changhe Ouyang, Yi Lu, Zai-Sheng Wu
"Y-shaped backbone-rigidified triangular DNA scaffold-directed stepwise movement of DNAzyme walker for sensitive microRNA imaging within living cells"
Anal. Chem. 91, 15678-15685 (2019) [PDF] [doi]
353 | Ryan J. Lake, Zhenglin Yang, JingJing Zhang, Yi Lu
"DNAzymes as Activity-Based Sensors for Metal Ions: Recent Applications, Demonstrated Advantages, Current Challenges, and Future Directions"
Acc. Chem. Res. 52, 3275-3286 (2019) [PDF] [doi]
352 | Noor Zaouri, Zhengfang Cui, Ana Sol Peinetti, Yi Lu, Pei-Ying Hong
"DNAzyme-based biosensor as a rapid and accurate verification tool to complement simultaneous enzyme-based media for E. coli detection"
Environ. Sci. Water Res. & Tech 5, 2260-2268 (2019) [PDF] [doi]
351 | Lin Xia, Ming-Jie Han, Lu Zhou, Aiping Huang, Zhaoya Yang, Tianyuan Wang, Fahui Li, Lu Yu, Changlin Tian, Zhongsheng Zang, Qing-Zheng Yang, Chenli Liu, Wenxu Hong, Yi Lu, Lital Alfonta, Jiangyun Wang
"S-Click Reaction for Isotropic Orientation of Oxidases on Electrodes to Promote Electron Transfer at Low Potentials"
Angew Chemie Int. Ed. 58, 16480-16484 (2019) [PDF] [doi]
350 | Yao Lin, Zhenglin Yang, Ryan J. Lake, Chengbin Zheng, Yi Lu
"Enzyme-Mediated Endogenous and Bioorthogonal Control of a DNAzyme Fluorescent Sensor for Imaging Metal Ions in Living Cells"
Angew Chemie Int. Ed. 58, 17061-17067 (2019) [PDF] [doi]
349 | Taylor D. Canady, Nantao Li, Lucas D. Smith, Yi Lu, Manish Kohli, Andrew M. Smith, Brian T. Cunningham
"Digital Resolution Detection of miRNA with Single Base Selectivity by Photonic Resonator Absorption Microscopy"
Proc. Natl. Acd. Sci. USA 116, 19362-19367 (2019) [PDF] [doi]
348 | Lele Li, Hang Xing, Jingjing Zhang, Yi Lu
"Functional DNA Molecules Enable Selective and Stimuli-Responsive Nanoparticles for Biomedical Applications"
Acc. Chem. Res. (special issue “Nanomedicine and Beyond”) 52, 2415-2426 (2019) [PDF] [doi]
347 | Wenjing Wang, Sha Yu, Shan Huang, Sai Bi, Heyou Han, Jian-Rong Zhang, Yi Lu, Jun-Jie Zhu
"Bioapplications of DNA nanotechnology at the solid–liquid interface"
Chem. Soc. Rev. 48, 4892-4920 (2019) [PDF] [doi]
346 | Kevin Hwang, Quanbing Mou, Ryan J. Lake, Mengyi Xiong, Brandalynn Holland, Yi Lu
"Metal-Dependent DNAzymes for the Quantitative Detection of Metal Ions in Living Cells: Recent Progress, Current Challenges, and Latest Results on FRET Ratiometric Sensors"
Inorg. Chem. 58, 13696-13708 (2019) [PDF] [doi]
345 | Jinqiong Xu, Xiujuan Qiao, Jingjing Zhang, Ni Cheng, Qinglin Sheng, Jianbin Zheng, Wei Cao, Tianli Yue, Yi Lu
"Point-of-care monitoring of intracellular glutathione and serum triglyceride levels using a versatile personal glucose meter"
Anal. Methods 11, 1849-1856 (2019) [PDF] [doi]
344 | Ambika Bhagi-Damodaran, Yi Lu
"The Periodic Table’s Impact on Bioinorganic Chemistry and Biology’s Selective use of Metal Ions"
in The Periodic Table II. Structures and Bonding (Special Issue on A Celebration of 150 years of the Periodic Table), vol 182, D. Michael P. Mingos (eds), Springer, Cham; pp. 153-173 (2019) [doi]
343 | Chang Liu, Yingjie Yu, Daquan Chen, Jian Zhao, Yang Yu, Lele Li, Yi Lu
"Cupredoxin engineered upconversion nanoparticles for ratiometric luminescence sensing of Cu2+"
Nanoscale Adv. 1, 2580-2585 (2019) [PDF] [doi]
342 | Nitya Sai Reddy Satyavolu, Kang Yong Loh, Li Huey Tan, Yi Lu
"Discovery of and Insights into DNA “Codes” for Tunable Morphologies of Metal Nanoparticles"
Small (Special issue on “DNA nanotechnology”) 15, 1900975 (2019) [PDF] [doi]
341 | Nitya Sai Reddy Satyavolu, Ana Sol Peinetti, Yiming Wang, Arzeena Sultana Ali, Jeffrey Wayjer Lin, Yi Lu
"Silver-Assisted Synthesis of High-indexed Palladium Tetrahexahedral Nanoparticles and their Morphological Variants"
Chem. Mater. 31, 2923-2929 (2019) [PDF] [doi]
340 | Jian Zhao, Hongqian Chu, Ya Zhao, Yi Lu, Lele Li
"A NIR Light-Gated DNA Nanodevice for Spatiotemporally Controlled Imaging of MicroRNA in Cells and Animals"
J. Am. Chem. Soc. 141, 7056–7062 (2019) [PDF] [doi]
339 | Evan N. Mirts, Ambika Bhagi-Damodaran, Yi Lu
"Understanding and Modulating Metalloenzymes with Unnatural Amino Acids, Non-Native Metal Ions, and Non-Native Metallocofactors"
Acc. Chem. Res. (Special Issue on "Artificial Metalloenzymes and Abiological Catalysis of Metalloenzymes") 52, 935-944 (2019) [PDF] [doi]
338 | Sergei A. Dikanov, Steven M. Berry, Yi Lu
"HYSCORE insights into the distribution of the unpaired spin density in an engineered CuA site in azurin and its His120Gly variant"
Inorg. Chem. 58, 4437-4445 (2019) [PDF] [doi]
337 | JingJing Zhang, Tian Lan, Yi Lu
"Molecular Engineering of Functional Nucleic Acid Nanomaterials toward In Vivo Applications"
Adv. Healthcare Mater. (special theme issue on Molecular Engineering, from Molecule to Medicine), 8, 1801158 (2019) [PDF] [doi]
336 | Chang Cui, Julian H. Reed, Evan N. Mirts, Yi Lu
"Design and Engineering of Heme Enzymes with O2-dependent Catalytic Activity"
in "Dioxygen-dependent Heme Enzymes", Metallobiology Series No. 13, Masao Ikeda-Saito and Emma Raven, Eds. The Royal Society of Chemistry, pp 37-62 (2019) [PDF] [doi]
2018
334 | Zhenglin Yang, Kang Yong Loh, Yueh-Te Chu, Ruopei Feng, Nitya Sai Reddy Satyavolu, Mengyi Xiong, Stephanie M. Nakamata Huynh, Kevin Hwang, Lele Li, Hang Xing, Xiaobing Zhang, Yann R. Chemla, Martin Gruebele, Yi Lu
"Optical Control of Metal Ion Probes in Cells and Zebrafish Using Highly Selective DNAzymes Conjugated to Upconversion Nanoparticles"
J. Am. Chem. Soc. 140, 17656-17665 (2018) [PDF] [doi]
333 | Sinan Sabuncu, Julian H. Reed, Yi Lu, Pierre Moënne-Loccoz
"Nitric Oxide Reductase Activity in Heme−Nonheme Binuclear Engineered Myoglobins through a One-Electron Reduction Cycle"
J. Am. Chem. Soc. 140, 17389-17393 (2018) [PDF] [doi]
332 | Yiming Wang, Nitya Sai Reddy Satyavolu, Yi Lu
"Sequence-specific control of inorganic nanomaterials morphologies by biomolecules"
Curr. Opin. Coll. Interf. Sci. 38, 158-169 (2018) [PDF] [doi]
331 | Evan N. Mirts, Igor D. Petrik, Parisa Hosseinzadeh, Mark J. Nilges, Yi Lu
"A designed heme-[4Fe-4S] metalloenzyme catalyzes sulfite reduction like the native enzyme"
Science 361, 1098-1101 (2018) [PDF] [doi] [news]
330 | Ze Yu, Wei Zhou, Ge Ma, Yunchao Li, Louzhen Fan, Xiaohong Li, Yi Lu
"Insights into the Competition between K+ and Pb2+ Binding to a G-Quadruplex and Discovery of a Novel K+–Pb2+–Quadruplex Intermediate"
J. Phys. Chem. B 122, 9382-9388 (2018) [PDF] [doi]
329 | Manjistha Mukherjee, Arnab Mukherjee, Ambika Bhagi-Damodaran, Yi Lu, Abhishek Dey
"O2 Reduction by Biosynthetic Models of Cytochrome c Oxidase: Insights into Role of Proton Transfer Residues from Perturbed Active Sites Models of CcO"
ACS Catalysis 8, 8915-8924 (2018) [PDF] [doi]
328 | John W. Peters, David N. Beratan, Brian Bothner, R. Brian Dyer, Caroline S. Harwood, Zachariah M. Heiden, Russ Hille, Anne K. Jones, Paul W. King, Yi Lu, Carolyn E. Lubner, Shelley D. Minteer, David W. Mulder, Simone Raugei, Gerrit J. Schut, Lance C. Seefeldt, Monika Tokmina-Lukaszewska, Oleg AZadvornyy, Peng Zhang, Michael W. W. Adams
"A new era for electron bifurcation"
Curr. Opin. Chem. Biol. 47, 32-38 (2018) [PDF] [doi]
326 | Ambika Bhagi-Damodaran, Julian Reed, Qianhong Zhu, Yelu Shid, Parisa Hosseinzadeh, Braddock A. Sandoval, Kevin A. Harnden, Shuyan Wang, Madeline R. Sponholtz, Evan N. Mirts, Sudharsan Dwaraknath, Yong Zhang, Pierre Moënne-Loccozd, Yi Lu
"Heme redox potentials hold the key to reactivity differences between nitric oxide reductase and heme-copper oxidase"
Proc. Natl. Acad. Sci. USA 115, 6195-6200 (2018) [PDF] [doi]
325 | JingJing Zhang, Hang Xing, Yi Lu
"Translating Molecular Detections into a Simple Temperature Test Using Target-Responsive Smart Thermometer"
Chem. Sci. 9, 3906-3910 (2018) [PDF] [doi]
324 | Nitya Sai Reddy Satyavolu, Nikou Pishevaresfahani, Li Huey Tan, Yi Lu
"DNA-encoded morphological evolution of bimetallic Pd@Au core-shell nanoparticles from a high-indexed core"
Nano Research 11, 4549–4561 (2018) [PDF] [doi]
323 | Marjorie Cepeda-Plaza, Claire E. McGhee, Yi Lu
"Evidence of a General Acid/Base Catalysis Mechanism in the 8-17 DNAzyme"
Biochemistry 57, 1517–1522 (2018) [PDF] [doi]
322 | Claire E. McGhee, Ryan Lake, Yi Lu
"Preparation of MetalloDNAzymes"
in "Artificial metalloenzymes and metalloDNAzymes in catalysis: From design to application", Montserrat Dieguez, and Jan-E. Backvall (eds.), Wiley-VCH; pp. 41-68 (2018) [PDF] [doi]
321 | Peiwen Wu, Yang Yu, Claire E. McGhee, Li Huey Tan, Abhijit Mishra, Gerard Wong, Yi Lu
"Applications of Synchrotron-based Spectroscopic Techniques in Studying Nucleic Acids and Nucleic Acid-based Nanomaterials"
in "Synchrotron Radiation in Materials Science: Light Sources, Techniques, and Applications", (Chunhai Fan and Zhentang Zhao, eds), Wiley-VCH; pp. 687-756 (2018) [PDF] [doi]
320 | Jian Zhao, Jinhong Gao, Wenting Xue, Zhenghan Di, Hang Xing, Yi Lu, Lele Li
"Upconversion Luminescence-Activated DNA Nanodevice for ATP Sensing in Living Cells"
J. Am. Chem. Soc. 140, 578-581 (2018) [PDF] [doi]
2017
319 | Jingjing Zhang, Lukas P Smaga, Nitya Sai Reddy Satyavolu, Jefferson Chan, Yi Lu
"DNA Aptamer-based Activatable Probes for Photoacoustic Imaging in Living Mice"
J. Am. Chem. Soc. 139, 17225-17228 (2017) [PDF] [doi] [news]
318 | Julian H. Reed, Yelu Shi, Qianhong Zhu, Saumen Chakraborty, Evan N. Mirts, Igor D. Petrik, Ambika Bhagi-Damodaran, Matthew Ross, Pierre Moenne-Loccoz, Yong Zhang, Yi Lu
"Manganese and Cobalt in the Nonheme Metal-binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-inactive Mechanism"
J. Am. Chem. Soc. 139, 12209-12218 (2017) [PDF] [doi]
317 | Zhenkun Wu, Huanhuan Fan, Nitya Sai Reddy Satyavolu, WenJing Wang, Ryan Lake, Jian-Hui Jiang, Yi Lu
"Imaging Endogenous Metal Ions in Living Cells Using a DNAzyme-Catalytic Hairpin Assembly Probe"
Angew. Chemie Int. Ed. 56, 8721-8725 (2017) [PDF] [doi]
316 | Marie Ramirez Cohen, Natanel Mendelman, Marina Radoul, Tiffany D. Wilson, Masha G. Savelieff, Herbert Zimmermann, Ilia Kaminker, Akiva Feintuch, Yi Lu, Daniella Goldfarb
"The thiolate spin population of type I copper in azurin derived from 33S hyperfine coupling"
Inorg. Chem. 56, 6163-6174 (2017) [PDF] [doi]
315 | Ambika Bhagi-Damodaran, Maximilian Kahle, Yelu Shi, Yong Zhang, Pia Adelroth, Yi Lu
"Insights into how heme reduction potentials modulate enzymatic activities of a myoglobin-based functional oxidase"
Angew. Chemie Int. Ed. 56, 6622-6626 (2017) [PDF] [doi]
314 | Wenjing Wang, Nitya Sai Reddy Satyavolu, Zhenkun Wu, Jian-Rong Zhang, Jun-Jie Zhu, Yi Lu
"Near-Infrared Photothermal Activated DNAzymes-Gold Nanoshells for Imaging Metal Ions in Living Cells"
Angew. Chemie Int. Ed. 56, 6798-6802 (2017) [PDF] [doi]
313 | Huanhuan Fan, Xiaobing Zhang, Yi Lu
"Recent advances in DNAzyme-based gene silencing"
Sci China Chem 60, 647-651 (2017) [PDF] [doi]
312 | Yi Lu
"The 'OK Molly Chemistry'"
Acc. Chem. Res. 50, (Special Issue: Holy Grails in Chemistry) 647-651 (2017) [PDF] [doi] [news]
311 | Claire E. McGhee, Kang Yong Loh, Yi Lu
"DNAzyme sensors for detection and imaging of metal ions in the environment and in living cells"
Curr. Opin. Biotech. 45, 191-201 (2017) [PDF] [doi]
310 | Hang Xing, Yugang Bai, Yunhao Bai, Li Huey Tan, Jing Tao, Benjamin Pedretti, Gretchen A. Vincil, Yi Lu, Steven C. Zimmerman
"Bottom-Up Strategy to Prepare Nanoparticles with a Single DNA Strand"
J. Am. Chem. Soc. 139, 3623-3626 (2017) [PDF] [doi]
309 | Debapriya Mazumdar, Tian Lan, Yi Lu
"'Dipstick' Colorimetric Detection of Metal Ions Based on Immobilization of DNAzyme and Gold Nanoparticles onto a Lateral Flow Device"
Biosensors and Biodetection: Methods and Protocols Volume 1: Optical-Based Detectors, Methods in Molecular Biology; Avraham Rasooly and Ben Prickril (Eds) 1571, 389-406 (2017) [PDF] [doi]
308 | Ambika Bhagi-Damodaran, Matthew A. Michael, Qianhong Zhu, Julian Reed, Braddock A. Sandoval, Evan N. Mirts, Saumen Chakraborty, Pierre Moenne-Loccoz, Yong Zhang, Yi Lu
"Why copper is preferred over iron for oxygen activation and reduction in heme-copper oxidases"
Nature Chemistry 9, 257-263 (2017) [PDF] [doi] [news]
307 | Yang Yu, Igor Petrik, Kelly N. Chacon, Parisa Hosseinzadeh, Honghui Chen, Ninian J. Blackburn, Yi Lu
"Effect of circular permutation on the structure and function of type 1 blue copper center in azurin"
Protein Science 26, 218-226 (2017) [PDF] [doi]
306 | Yang Yu, Chang Cui, Jiangyun Wang, Yi Lu
"Biosynthetic Approach to Modeling and Understanding Metalloproteins using Unnatural Amino Acids"
Science China Chem 60, 188-200 (2017) [PDF] [doi]
305 | Kevin M. Clark, Shiliang Tian, Wilfred A. van der Donk, Yi Lu
"Probing the role of the backbone carbonyl interaction with the CuA center in azurin by replacing the peptide bond with an ester linkage"
Chem. Comm. 53, 224-227 (2017) [PDF] [doi]
2016
304 | Nitya Sai Reddy Satyavolu, Li Huey Tan, Yi Lu
"DNA-Mediated Morphological Control of Pd-Au Bimetallic Nanoparticles"
J. Am. Chem. Soc. 138, (50) 16542-16548 (2016) [PDF] [doi]
303 | Yugang Bai, Xinxin Feng, Hang Xing, Yanhua Xu, Boo Kyung Kim, Noman Baig, Tianhui Zhou, Andrew A. Gewirth, Yi Lu, Eric Oldfield, Steven C. Zimmerman
"A Highly Efficient Single-Chain Metal-Organic Nanoparticle Catalyst, for Alkyne-Azide 'Click' Reactions in Water and in Cells"
J. Am. Chem. Soc. 138, (35) 11077-11080 (2016) [PDF] [doi]
301 | Ambika Bhagi-Damodaran, Igor Petrik, Yi Lu
"Using Biosynthetic Models of Heme-Copper Oxidase and Nitric Oxide Reductase in Myoglobin to Elucidate Structural Features Responsible for Enzymatic Activities"
Isr. J. Chem. 56, (special issue on New Frontiers in Bioinorganic Chemistry) 773-790 (2016) [PDF] [doi]
300 | Ambika Bhagi-Damodaran, Parisa Hosseinzadeh, Evan Mirts, Julian Reed, Igor D. Petrik, Yi Lu
"Design of Heteronuclear Metalloenzymes"
Methods in Enzymology 580, (Peptide, Protein and Enzyme Design) 501-537 (2016) [PDF] [doi]
299 | Flavia Nastri, Marco Chino, Ornella Maglio, Ambika Bhagi-Damodaran, Yi Lu, Angela Lombardi
"Design and Engineering of Artificial Oxygen-Activating Metalloenzymes"
Chem. Soc. Rev. 45, 5020-5054 (2016) [PDF] [doi]
298 | Hang Xing, Kevin Hwang, Yi Lu
"Recent Developments of Liposomes as Nanocarriers for Theranostic Applications"
Theranostics 6, (Thematic Issue on NanoTheranostics) 1336-1352 (2016) [PDF] [doi]
297 | JingJing Zhang, FangFang Cheng, JingJing Li, Jun-Jie Zhu, Yi Lu
"Fluorescent nanoprobes for metal ion sensing and imaging: recent advances and future perspectives"
Nano Today 11, (3) 309-329 (2016) [PDF] [doi]
296 | Parisa Hosseinzadeh, Shiliang Tian, Nicholas M. Marshall, James Hemp, Timothy Mullen, Mark J. Nilges, Yi-Gui Gao, Howard Robinson, David A. Stahl, Robert B. Gennis, Yi Lu
"A Purple Cupredoxin from Nitrosopumilus maritimus Containing a Mononuclear Type 1 Copper Center with an Open Binding Site"
J. Am. Chem. Soc. 138, (20) 6324-6327 (2016) [PDF] [doi]
295 | Kevin Hwang, Parisa Hosseinzadeh, Yi Lu
"Biochemical and biophysical understanding of metal ion selectivity of DNAzymes"
Inorg. Chim. Acta 452, 12-24 (2016) [PDF] [doi]
294 | Hang Xing, Ji Li, Weidong Xu, Kevin Hwang, Peiwen Wu, Qian Yin, Zhensheng Li, Jianjun Cheng, Yi Lu
"The Effects of Spacer Length and Composition on Aptamer-Mediated Cell-Specific Targeting with Nanoscale PEGylated Liposomal Doxorubicin"
ChemBioChem 17, (12) 1111-1117 (2016) [PDF] [doi]
291 | Shefali Chauhan, Parisa Hosseinzadeh, Yi Lu, Ninian Blackburn
"Stopped-Flow Studies of the Reduction of the Copper Centers Suggest a Bifurcated Electron Transfer Pathway in Peptidylglycine Monooxygenase"
Biochemistry 55, 2008-2021 (2016) [PDF] [doi]
290 | Tian Lan, Jingjing Zhang, Yi Lu
"Transforming the blood glucose meter into a general healthcare meter for in vitro diagnostics in mobile health"
Biotechnology Advances 34, 31-41 (2016) [PDF] [doi]
289 | Shiliang Tian, Jing Liu, Ryan E. Cowley, Parisa Hosseinzadeh, Nicholas M. Marshall, Yang Yu, Howard Robinson, Mark J. Nilges, Ninian J. Blackburn, Edward I. Solomon, Yi Lu
"Reversible S-Nitrosylation in an Engineered Azurin"
Nature Chemistry 8, 670-677 (2016) [PDF] [doi]
288 | Parisa Hosseinzadeh, Evan N. Mirts, Thomas D. Pfister, Yi-Gui Gao, Christopher Mayne, Howard Robinson, Emad Tajkhorshid, Yi Lu
"Enhancing Mn(II)-binding and manganese peroxidase activity in a designed cytochrome c peroxidase through fine-tuning secondary sphere interactions"
Biochemistry 55, (10) 1494-1502 (2016) [PDF] [doi]
287 | Igor D. Petrik, Roman Davydov, Matthew Ross, Xuan Zhao, Brian Hoffman, Yi Lu
"Spectroscopic and crystallographic evidence for the role of a water-containing hydrogen bonding network in oxidase activity of an engineered myoglobin"
Journal of the American Chemical Society 138, (4) 1134-1137 (2016) [PDF] [doi] [news]
286 | Hang Xing, Caroline Luowen Zhang, George Ruan, Jingjing Zhang, Kevin Hwang, Yi Lu
"Multimodal Detection of a Small Molecule Target Using Stimuli-Responsive Liposome Triggered by Aptamer-Enzyme Conjugate"
Analytical Chemistry 88, (3) 1506-1510 (2016) [PDF] [doi]
285 | Liuming Yan, Yi Lu, Xuejiao Li
"A Density Functional Theory Protocol for the Calculation of Redox Potentials of Copper Complexes"
Phys. Chem. Chem. Phys. 18, 5529-5536 (2016) [PDF] [doi]
284 | Parisa Hosseinzadeh, Yi Lu
"Design and Fine-tuning Redox Potentials of Metalloproteins Involved in Electron Transfer in Bioenergetics"
Biochem. Biophys. Acta (BBA) - Bioenergetics 1857, 557-581 (2016) [PDF] [doi]
283 | Jingjing Zhang, Yu Xiang, Miao Wang, Ananda Basu, Yi Lu
"Dose-Dependent Response of Personal Glucose Meters to Nicotinamide Coenzymes: Applications to Point-of-Care Diagnostics of Many Non-Glucose Targets in a Single Step"
Angew Chemie Int. Ed. 55, (2) 732-736 (2016) [PDF] [doi] [news]
282 | Parisa Hosseinzadeh, Nicholas M. Marshall, Kelly N. Chacon, Yang Yu, Mark J. Nilges, Siu Yee New, Ninian J. Blackburn, Yi Lu
"Design of a Single Protein that Spans the Entire 2V Range of Physiological Redox Potentials"
Proc. Natl. Acad. Scie. 113, (2) 262-267 (2016) [PDF] [doi] [news]
2015
281 | Li Huey Tan, Yuan Yue, Nitya Sai Reddy Satyavolu, Arzeena Sultana Ali, Zidong Wang, Yuqing Wu, Yi Lu
"A mechanistic insight into DNA-guided control of nanoparticle morphologies"
J. Am. Chem. Soc. 137, (45) 14456-14464 (2015) [PDF] [doi]
280 | Yang Yu, Chang Cui, Xiaohong Liu, Igor Petrik, Jiangyun Wang, Yi Lu
"A Designed Metalloenzyme Achieving the Catalytic Rate of a Native Enzyme"
J. Am. Chem. Soc. 137, (36) 11570-11573 (2015) [PDF] [doi] [news]
279 | Seyed-Fakhreddin Torabi, Yi Lu
"Identification of the same Na+-specific DNAzyme motif from two in vitro selections at different conditions"
J. Mol. Evolution (Special Edition to Celebration SELEX for 25 years 81, (5) 225-234 (2015) [PDF] [doi]
278 | Yugang Bai, Hang Xing, Peiwen Wu, Xinxin Feng, Jennifer M. Lee, Xin Yi Phang, Yi Lu, Steven C. Zimmerman
"Chemical Control over Cellular Uptake of Organic Nanoparticles by Fine Tuning Surface Functional Groups"
ACS Nano 9, (10) 10227-20236 (2015) [PDF] [doi]
277 | Saumen Chakraborty, Michael J. Polen, Kelly N. Chacon, Tiffany D. Wilson, Yang Yu, Julian Reed, Mark J. Nilges, Ninian J. Blackburn, Yi Lu
"Binuclear CuA Formation in Biosynthetic Models of CuA in Azurin Proceeds via a Novel Cu(Cys)2His Mononuclear Copper Intermediate"
Biochemistry 54, (39) 6071-6081 (2015) [PDF] [doi]
276 | Sohini Mukherjee, Arnab Mukherjee, Ambika Bhagi-Damodaran, Manjistha Mukherjee, Yi Lu, Abhishek Dey
"A Biosynthetic Model of Cytochrome c Oxidase as an Electrocatalysts for O2 Reduction"
Nature Communication 6, Article 8467 (2015) [PDF] [doi]
275 | Roger M. Pallares, Say Li Kong, Tan Hui Ru, Nguyên T.K. Thanh, Yi Lu, Xiaodi Su
"A plasmonic nanosensor with inverse sensitivity for circulating cell-free DNA quantification"
Chem. Comm. 51, 14524-14527 (2015) [PDF] [doi]
274 | Saumen Chakraborty, Julian Reed, J. Timothy Sage, Nicole C. Branagan, Igor D. Petrik, Kyle D. Miner, Michael Y. Hu, Jiyong Zhao, E. Ercan Alp, Yi Lu
"Recent Advances in Biosynthetic Modeling of Nitric Oxide Reductases and Insights Gained from Nuclear Resonance Vibrational and Other Spectroscopic Studies"
Inorg. Chem. 54, 9317-9329 (2015) [PDF] [doi]
273 | Chunmei Gu, Tian Lan, Hanchang Shi, Yi Lu
"Portable Detection of Melamine in Milk Using a Personal Glucose Meter Based on an in Vitro Selected Structure-Switching Aptamer"
Analytical Chemistry 87, 7676-7682 (2015) [PDF] [doi] [news]
272 | Ambika Bhagi-Damodaran, Yi Lu
"The Q, Compound Q is Finally Deciphered"
Inorganic Chemistry Frontiers 2, 824-826 (2015) [PDF] [doi]
271 | Jingjing Zhang, Yu Xiang, Donna E. Novak, George E. Hoganson, Junjie Zhu, Yi Lu
"Using Personal Glucose Meter and Alkaline Phosphatase for Point-of-care Quantification of Galactose-1-Phosphate Uridyltransferase in Clinical Galactosemia Diagnosis"
Chem. Asian J. 10, (10) 2221-2227 (2015) [PDF] [doi]
270 | Tingjie Song, Longhua Tang, Li Huey Tan, Xiaojing Wang, Nitya Sai Reddy Satyavolu, Hang Xing, Zidong Wang, Jinghong Li, Haojun Liang, Yi Lu
"DNA-Encoded Tuning of Geometric and Plasmonic Properties of Nanoparticles Growing from Gold Nanorod Seeds"
Angewandte Chemie International Edition 54, 8114-8118 (2015) [PDF] [doi]
269 | Yang Yu, Qing Zhou, Li Wang, Xiaohong Liu, Wei Zhang, Meirong Hu, Jianshu Dong, Jiasong Li, Xiaoxuan Lv, Hanlin Ouyang, Han Li, Feng Gao, Weimin Gong, Yi Lu, Jiangyun Wang
"Significant improvement of oxidase activity through the genetic incorporation of a redox-active unnatural amino acid"
Chemical Science 6, 3881-3885 (2015) [PDF] [doi]
268 | Aimee M. Gall, Benito J. Marinas, Yi Lu, Joanna L. Shisler
"Waterborne viruses: A barrier to safe drinking water"
PLOS Pathogens 11, (6) (2015) [PDF] [doi]
267 | Mi Hee Lim, Yi Lu
"Editorial overview: Bioinorganic chemistry: Bioinorganic catalysis for renewable energy"
Current Opinion in Chemical Biology 25, vii-viii (2015) [PDF] [doi]
266 | Seyed-Fakhreddin Torabi, Peiwen Wu, Claire E. McGhee, Lu Chen, Kevin Hwang, Nan Zheng, Jianjun Cheng, Yi Lu
"In vitro selection of a sodium-specific DNAzyme and its application in intracellular sensing"
Proc. Natl. Acad. Sci. 112, (19) 5903-5908 (2015) [PDF] [doi] [news]
265 | Le-Le Li, Yi Lu
"Regiospecific Hetero-Assembly of DNA-Functionalized Plasmonic Upconversion Superstructures"
Journal of the American Chemical Society 137, (16) 5272-5275 (2015) [PDF] [doi]
264 | Yang Yu, Xiaoxuan Lv, Jiasong Li, Qing Zhou, Chang Cui, Parisa Hosseinzadeh, Arnab Mukherjee, Mark J. Nilges, Jiangyun Wang, Yi Lu
"Defining the Role of Tyrosine and Rational Tuning of Oxidase Activity by Genetic Incorporation of Unnatural Tyrosine Analog"
Journal of the American Chemical Society 137, (14) 4594-4597 (2015) [PDF] [doi]
263 | Ning Li, Xiaodi Su, Yi Lu
"Nanomaterial-based Biosensors using Dual Transducing Elements for Solution Phase Detection"
Analyst 140, 2916-2943 (2015) [PDF] [doi]
262 | Li Gao, Le-Le Li, Xiaolong Wang, Peiwen Wu, Yang Cao, Bo Liang, Xin Li, Yuanwei Lin, Yi Lu, Xuefeng Guo
"Graphene-DNAzyme Junctions: A platform for Metal Ion Detection with Ultrahigh Sensitivity"
Chemical Science 6, 2469-2473 (2015) [PDF] [doi]
261 | Tian Lan, Yu Xiang, Yi Lu
"Detection of protein biomarkers using a blood glucose meter (BGM)"
in Mobile Health Technologies: Methods and Protocols, Avraham Rasooly and Keith Herold (Eds)99-110 (2015) [doi]
260 | Ole Farver, Parisa Hosseinzadeh, Nicholas M. Marshall, Scot Wherland, Yi Lu, Israel Pecht
"Long-Range Electron Transfer in Engineered Azurins Exhibits Marcus Inverted Region Behavior"
The Journal of Physcal Chemstry Letters 6, 100-105 (2015) [PDF] [doi]
2014
259 | Jiangjiexing Wu, Li Huey Tan, Kevin Hwang, Hang Xing, Peiwen Wu, Wei Li, Yi Lu
"DNA Sequence-Dependent Morphological Evolution of Silver Nanoparticles and Their Optical and Hybridization Properties"
Journal of the American Chemical Society 136, 15195-15202 (2014) [PDF] [doi]
258 | Kevin Hwang, Peiwen Wu, Taejin Kim, Lei Lei, Shiliang Tian, Yingxiao Wang, Yi Lu
"Photocaged DNAzymes as a General Method for Sensing Metal Ions in Living Cells"
Angewandte Chemie International Edition 53, 13798-13802 (2014) [PDF] [doi]
257 | Xiaohong Liu, Li Jiang, Jiasong Li, Li Wang, Yang Yu, Qing Zhou, Xiaoxuan Lv, Weimin Gong, Yi Lu, Jiangyun Wang
"Significant Expansion of Fluorescent Protein Sensing Ability through the Genetic Incorporation of Superior Photo-Induced Electron-Transfer Quenchers"
Journal of the American Chemical Society 136, 13094-13097 (2014) [PDF] [doi]
256 | Jing Liu, Katlyn Meier, Shiliang Tian, Jun-long Zhang, Hongchao Guo, Charles E Schulz, Howard Robinson, Mark J. Nilges, Eckard Munck, Yi Lu
"Redesigning the Blue Copper Azurin into a Redox-active Mononuclear Non-heme Iron Protein: Preparation and Study of Fe(II)-M121E Azurin"
Journal of the American Chemical Society 136, 12337-12344 (2014) [PDF] [doi]
255 | Ambika Bhagi-Damodaran, Igor D. Petrik, Nicholas M. Marshall, Howard Robinson, Yi Lu
"Systematic Tuning of Heme Redox Potentials and its Effects on O2 Reduction Rates in a Designed Oxidase in Myoglobin"
Journal of the American Chemical Society 136, 11882-11885 (2014) [PDF] [doi]
254 | Peiwen Wu, Yang Yu, Claire E. McGhee, Li Huey Tan, Yi Lu
"Applications of Synchrotron-based Spectroscopic Techniques in Studying Nucleic Acids and Nucleic Acid-Functionalized Nanomaterials"
Adv. Mater. 26, 7849-7872 (2014) [PDF] [doi]
253 | Kyle D. Miner, Thomas D. Pfister, Parisa Hosseinzadeh, Nadime Karaduman, Lynda J. Donald, Peter C. Loewen, Yi Lu, Anabella Ivancich
"Identifying the Elusive Sites of Tyrosyl Radicals in Cytochrome c Peroxidase: Implications for Oxidation of Substrates Bound at a Site Remote from the Heme"
Biochemistry 53, 3781-3789 (2014) [PDF] [doi]
252 | . Li Huey Tan, Hang Xing, Yi Lu
"DNA as a Powerful Tool for Morphology Control, Spatial Positioning and Dynamic Assembly of Nanoparticles"
Accounts of Chemical Research 47, 1881-1890 (2014) [PDF] [doi]
251 | Yugang Bai, Hang Xing, Gretchen A. Vincil, Jennifer Lee, Essence Henderson, Yi Lu, Gabriel Lemcoff, Steve Zimmerman
"Practical Synthesis of Water-soluble Organic Nano-particles with a Single Reactive Group and a Functional Carrier Scaffold"
Chemical Science 5, 2862-2868 (2014) [PDF] [doi]
250 | Zhaojuan Zhou, Yu Xiang, Aijun Tong, Yi Lu
"Simple and Efficient Method to Purify DNA-Protein Conjugates and Its Sensing Applications"
Analytical Chemistry 86, 3869-3875 (2014) [PDF] [doi]
249 | Yu Xiang, Tian Lan, Yi Lu
"Using the widely available blood glucose meter to monitor insulin and HbA1c"
Journal of Diabetes Science and Technology 8, 855-858 (2014) [PDF] [doi]
248 | Saumen Chakraborty, Parisa Hosseinzadeh, Yi Lu
"Metalloprotein Design & Engineering"
in "Encyclopedia of Inorganic and Bioinorganic Chemistry", R.A. Scott, ed.; John Wiley and Sons, Ltd.: Chichester; pp. 1-51 (2014) [PDF] [doi]
247 | Yi Lu
"Uranium extraction: Coordination chemistry in the ocean"
Nature Chemistry 6, (5) 175-177 (2014) [PDF] [doi]
246 | Siu Yee New, Khin Moh Moh Aung, Gek Liang Lim, Shuzhen Hong, Si Kee Tan, Yi Lu, Edwin Cheung, Xiaodi Su
"Fast Screening of Ligand-Protein Interactions based on Ligand-Induced Protein Stabilization of Gold Nanoparticles"
Analytical Chemistry 86, 2361-2370 (2014) [PDF] [doi]
245 | Yang Yu, Arnab Mukherjee, Mark J. Nilges, Parisa Hosseinzadeh, Kyle D. Miner, Yi Lu
"Direct EPR Observation of a Tyrosyl Radical in a Functional Oxidase Model in Myoglobin during both H2O2 and O2 Reactions"
J. Am. Chem. Soc. 136, (4) 1174-1177 (2014) (available online) [PDF] [doi]
244 | Hang Xing, Kevin Hwang, Ji Li, Seyed-Fakhreddin Torabi, Yi Lu
"DNA Aptamer Technology for Future Personalized Medicine"
Curr. Opin. Chem. Eng. 4, 79-87 (2014) [PDF] [doi]
243 | Hirotoshi Matsumura, Takahiro Hayashi, Saumen Chakraborty, Yi Lu, Pierre Moenne-Loccoz
"The production of nitrous oxide (N2O) by the heme/nonheme diiron center of engineered myoglobins (FeBMbs) proceeds through a trans iron-nitrosyl dimer"
J. Am. Chem. Soc. 136, (6) 2420-2431 (2014) (available online) [PDF] [doi]
242 | Igor D. Petrik, Jing Liu, Yi Lu
"Metalloenzyme Design and Engineering through Strategic Modifications of Native Protein Scaffolds"
Curr. Opin. Chem. Biol. 19, 67-75 (2014) [PDF] [doi]
241 | Ying-Wu Lin, Jiangyun Wang, Yi Lu
"Functional tuning and expanding of myoglobin by rational protein design"
Science China Chemistry 57, (3) 346-355 (2014) [PDF] [doi]
240 | Ilia Kaminker, Tiffany D Wilson, Masha G Savelieff; Yonatan Hovav, Herbert Zimmermann, Yi Lu, Daniella Goldfarb
"Correlating nuclear frequencies by two-dimensional ELDOR-detected NMR spectroscopy"
J. Mag. Reson. 240, 77-89 (2014) [PDF] [doi]
239 | Nathan A. Sieracki, Shiliang Tian, Ryan G. Hadt, Jun-Long Zhang, Julia S. Woertink, Mark J. Nilges, Furong Sun, Edward I. Solomon, Yi Lu
"Copper-sulfenate complex from oxidation of a cavity mutant of Pseudomonas aeruginosa azurin"
Proceedings of the National Academy of Science of the United States of America 111, (3) 924-929 (2014) [PDF] [doi]
238 | Jing Liu, Saumen Chakraborty, Parisa Hosseinzadeh, Yang Yu, Shiliang Tian, Igor Petrik, Ambika Bhagi, Yi Lu
"Metalloproteins Containing Cytochrome, Iron-sulfur or Copper Redox Centers"
Chem. Rev.(2014) [PDF] [doi]
237 | Saumen Chakraborty, Julian Reed, Matthew Ross, Mark J. Nilges, Igor D. Petrik, Soumya Ghosh, Sharon Hammes-Schiffer, J. Timothy Sage, Yong Zhang, Charles E. Schulz, Yi Lu
"Spectroscopic and Computational Study of a Non-heme Iron-Nitrosyl Center in a Biosynthetic Model of Nitric Oxide Reductases in Myoglobin Containing Zn-protoporphyrin IX: Support for the Trans Mechanism of NO Reduction"
Angew. Chem., Int. Ed. 53, (9) 2417-2421 (2014) (available online) [PDF] [doi]
236 | Yu Xiang, Yi Lu
"DNA as Sensors and Imaging Agents for Metal Ions"
Inorganic Chemistry(2014) [PDF] [doi]
235 | Kevin M Clark, Yang Yu, Wilfred A van der Donk, Ninian Blackburn, Yi Lu
"Modulating the Copper-Sulfur Interaction in Type 1 Blue Copper Azurin by Replacing Cys112 with Nonproteinogenic Homocysteine"
Inorg. Chem. Frontiers 1, (2) 153-158 (2014) [PDF] [doi]
234 | Lauren A. Denofrio-Corrales, Antoinette Burton Yi Lu (Mary-Ann Winkelmes, Kyle Mays eds.)
"From Desk to Bench, Linking Students' Interests to Science Curricula"
Illinois Sampler: Teaching on the Prairie, 27-33 (2014)
233 | Seyed-Fakhreddin Torabi, Yi Lu
"Functional DNA Nanomaterials for Sensing and Imaging in Living Cells"
Curr. Opin. Biotech. 28, 88-95 (2014) [PDF] [doi]
2013
232 | Li Huey Tan, Hang Xing, Hongyu Chen, Yi Lu
"Facile and efficient preparation of anisotropic DNA-functionalized gold nanoparticles and their regioselective assembly"
Journal of the American Chemical Society(135) 17675-17678 (2013) [PDF] [doi]
231 | Longhua Tang, Ik Su Chun, Zidong Wang, Jinghong Li, Xiuling Li, Yi Lu
"DNA Detection using Plasmonic Enhanced Near-Infrared Photoluminescence of Gallium Arsenide"
Analytical Chemistry 85, (20) 9522-9527 (2013) [PDF] [doi]
230 | Hannah A. DeBerg, Benjamin H. Blehm, Janet Sheung, Andrew R. Thompson, Carol S. Bookwalter, Seyed F. Torabi, Trina A. Shroer, Christopher L. Berger, Yi Lu, Kathleen M. Trybus, Paul R. Selvin
"Motor Domain Phosphorylation Modulates Kinesin-1 Transport"
Journal of Biological Chemistry 288, 32612-32621 (2013) [PDF] [doi]
229 | Yu Xiang, Peiwen Wu, Li Huey Tan, Yi Lu
"DNAzyme-Functionalized Gold Nanoparticles for Biosensing"
Advances in Biochemical Engineering/Biotechnology, Springer Berlin Heidelberg; pp. 1-28 (2013) [PDF] [doi]
228 | Ming-Li Tsai, Ryan G. Hadt, Nicholas M. Marshall, Tiffany D. Wilson, Yi Lu, Edward I. Solomon
"Axial interactions in the mixed-valent CuA active site and role of the axial methionine in electron transfer"
Proceedings of the National Academy of Sciences 110, 14658-14663 (2013) [PDF] [doi]
227 | Weichen Xu, Hang Xing, Yi Lu
"A smart T1-weighted MRI contrast agent for uranyl cations based on a DNAzyme-gadolinium conjugate"
Analyst 138, (21) 6266-6269 (2013) [PDF] [doi]
226 | Tingting Chen, Yihui Hu, Yao Cen, Xia Chu, Yi Lu
"A Dual-Emission Fluorescent Nanocomplex of Gold Clusters Decorated Silica Particle for Live Cell Imaging of Highly Reactive Oxygen Species"
Journal of the American Chemical Society 135, 11595-11601 (2013) [PDF] [doi]
225 | Marjorie Cepeda-Plaza, Eric L. Null, Yi Lu
"Metal Ion as Both a Cofactor and a Probe of Metal- binding Sites in a Uranyl-Specific DNAzyme: a Uranyl Photocleavage Study"
Nucleic Acids Res. 41, (20) 9361-9370 (2013) [PDF] [doi]
224 | Hang Xing, Li Tang, Xujuan Yang, Kevin Hwang, Wendan Wang, Qian Yin, Ngo Yin Wong, Lawrence W. Dobrucki, Norio Yasui, John Katzenellenbogen, William Helferich, Jianjun Cheng, Yi Lu
"Selective Delivery of an Anticancer Drug with Aptamer-Functionalized Liposomes to Breast Cancer Cells in Vitro and in Vivo"
J. Mater. Chem. B 1, (39) 5288-5297 (2013) [PDF] [doi]
223 | Hui Wei, Stephen House, Jiangjiexing Wu, Jiong Zhang, Zidong Wang, Ying He, Yi-Gui Gao, Howard Robinson, Wei Li, Jian-Min Zuo, Ian M. Robertson, Yi Lu
"Enhanced and Tunable Fluorescent Quantum Dots within a Single Crystal of Protein"
Nano Research 6, (9) 627-634 (2013) [PDF] [doi]
222 | Ole Farver, Nicholas M. Marshall, Scot Wherland, Yi Lu, Israel Pecht
"Designed azurins show lower reorganization free energies for intraprotein electron transfer"
Proceedings of the National Academy of Sciences 110, 10536-10540 (2013) [PDF] [doi]
221 | Le-Le Li, Mengying Xie, Jie Wang, Xinyang Li, Cheng Wang, Quan Yuan, Dai-Wen Pang, Yi Lu, Weihong Tan
"A vitamin-responsive mesoporous nanocarrier with DNA aptamer-mediated cell targeting"
Chem. Commun. 49, (52) 5823-5825 (2013) [PDF] [doi]
220 | Peiwen Wu, Kevin Hwang, Tian Lan, Yi Lu
"A DNAzyme-Gold Nanoparticle Probe for Uranyl Ion in Living Cells"
Journal of the American Chemical Society 135, 5254-5257 (2013) [PDF] [doi]
219 | Zidong Wang, Madurai Srinivasan Bharathi, Ramanarayan Hariharaputran, Hang Xing, Longhua Tang, Jinghong Li, Yong-Wei Zhang, Yi Lu
"pH-Dependent Evolution of Five-Star Gold Nanostructures: An Experimental and Computational Study"
ACS Nano 7, 2258-2265 (2013) [PDF] [doi]
218 | Ngo Yin Wong, Hang Xing, Li Huey Tan, Yi Lu
"Nano-Encrypted Morse Code: A Versatile Approach to Programmable and Reversible Nanoscale Assembly and Disassembly"
Journal of the American Chemical Society 135, 2931-2934 (2013) [PDF] [doi] [news]
217 | Le-Le Li, Peiwen Wu, Kevin Hwang, Yi Lu
"An Exceptionally Simple Strategy for DNA-Functionalized Up-Conversion Nanoparticles as Biocompatible Agents for Nanoassembly, DNA Delivery, and Imaging"
Journal of the American Chemical Society 135, 2411-2414 (2013) [PDF] [doi] [news]
216 | Nicholas M. Marshall, Kyle D. Miner, Tiffany D. Wilson, Yi Lu
"Rational Design of Protein Cages for Alternative Enzymatic Functions"
in "Coordination Chemistry in Protein Cages: Principles, Design, and Applications", Takafumi Ueno, Yoshihito Watanabe, eds.; John Wiley & Sons; pp. 111-150 (2013) [PDF] [doi]
215 | LeLe Li, Yi Lu
"Functional DNA-Integrated Nanomaterials for Biosensing"
in "DNA Nanotechnology: From Structure to Function", Chunhai Fan (ed.), Springer-Verlag Berlin Heidelberg; pp. 227-305 (2013) [PDF] [doi]
214 | Yi Lu, Saumen Chakraborty, Kyle D. Miner, Tiffany D. Wilson, Arnab Mukherjee, Yang Yu, Jing Liu, Nicholas M. Marshall
"Metalloprotein Design"
in "Comprehensive Inorganic Chemistry II", Elsevier Science; pp. 565-593 (2013) [doi]
213 | Yu Xiang, Yi Lu
"An Invasive DNA Approach toward a General method for Portable Quantification of Metal Ions using a Personal Glucose Meter"
Chem. Commun. 49, (6) (Nucleic Acids: new life, new materials - joint Chem. Comm., Org. Biomol. Chem., and RSC Adv. web themed issue) 585-587 (2013) [PDF] [doi]
2012
210 | Yi Lu, Nicholas Marshall
"Redox Potential"
in "Encyclopedia of Biophysics", In Robers G. (Ed.), Vol. 4, Springer-Verlag Berlin Heidelberg; pp. 2207-2211 (2012)
208 | Kazuyo Shigeta, Ying He, Erick Sutanto, Somi Kang, An-Phong Le, Ralph G. Nuzzo, Andrew G. Alleyne, Placid M. Ferreira, Yi Lu, John A. Rogers
"Functional Protein Microarrays by Electrohydrodynamic Jet Printing"
Analytical Chemistry 84, 10012-10018 (2012) [PDF] [doi]
207 | Ryan G. Hadt, Ning Sun, Nicholas M. Marshall, Keith O. Hodgson, Britt Hedman, Yi Lu, Edward I. Solomon
"Spectroscopic and DFT Studies of Second-Sphere Variants of the Type 1 Copper Site in Azurin: Covalent and Nonlocal Electrostatic Contributions to Reduction Potentials"
Journal of the American Chemical Society 134, 16701-16716 (2012) [PDF] [doi]
206 | Le-Le Li, Pinghua Ge, Paul R. Selvin, Yi Lu
"Direct Detection of Adenosine in Undiluted Serum Using a Luminescent Aptamer Sensor Attached to a Terbium Complex"
Analytical Chemistry 84, 7852-7856 (2012) [PDF] [doi]
205 | Zidong Wang, Longhua Tang, Li Huey Tan, Jinghong Li, Yi Lu
"Discovery of the DNA "Genetic Code" for Abiological Gold Nanoparticle Morphologies"
Angewandte Chemie International Edition 51, 9078-9082 (2012) [PDF] [doi] [news]
204 | Le-Le Li, Qian Yin, Jianjun Cheng, Yi Lu
"Polyvalent Mesoporous Silica Nanoparticle-Aptamer Bioconjugates Target Breast Cancer Cells"
Advanced Healthcare Materials 1, 567-572 (2012) [PDF] [doi]
203 | Zhenghao Yang, Zhipeng Liu, Yuncong Chen, Xiaoqing Wang, Weijiang He, Yi Lu
"A new ratiometric and colorimetric chemosensor for cyanide anion based on Coumarin-hemicyanine hybrid"
Organic & Biomolecular Chemistry 10, 5073-5076 (2012) [PDF] [doi]
202 | Hong Liu, Yu Xiang, Yi Lu, Richard M. Crooks
"Aptamer-Based Origami Paper Analytical Device for Electrochemical Detection of Adenosine"
Angewandte Chemie International Edition 51, 6925-6928 (2012) [PDF] [doi]
201 | Kyle D. Miner, Arnab Mukherjee, Yi-Gui Gao, Eric L. Null, Igor D. Petrik, Xuan Zhao, Natasha Yeung, Howard Robinson, Yi Lu
"A Designed Functional Metalloenzyme that Reduces O2 to H2O with Over One Thousand Turnovers"
Angewandte Chemie International Edition 51, 5589-5592 (2012) [PDF] [doi] [news]
200 | Le-Le Li, Ruobing Zhang, Leilei Yin, Kezhi Zheng, Weiping Qin, Paul R. Selvin, Yi Lu
"Biomimetic Surface Engineering of Lanthanide-Doped Upconversion Nanoparticles as Versatile Bioprobes"
Angewandte Chemie International Edition 51, 6121-6125 (2012) [PDF] [doi]
199 | JungHeon Lee, Zidong Wang, Yi Lu
"DNAzyme-Based Sensing for Metal Ions in Ocean Platform"
in "Molecular Biological Technologies for Ocean Sensing", Springer Protocols Handbooks, Sonia M. Tiquia-Arashiro, ed.; Humana Press: New York, NY; pp. 103-116 (2012) [doi]
198 | Hang Xing, Ngo Yin Wong, Yu Xiang, Yi Lu
"DNA aptamer functionalized nanomaterials for intracellular analysis, cancer cell imaging and drug delivery"
Current Opinion in Chemical Biology 16, 429-435 (2012) [PDF] [doi]
197 | Xiaohong Liu, Yang Yu, Cheng Hu, Wei Zhang, Yi Lu, Jiangyun Wang
"Significant Increase of Oxidase Activity through the Genetic Incorporation of a Tyrosine-Histidine Cross-Link in a Myoglobin Model of Heme-Copper Oxidase"
Angewandte Chemie International Edition 51, 4312-4316 (2012) [PDF] [doi]
195 | Weiqiao Zeng, Alexander Barabanschikov, Ningyan Wang, Yi Lu, Jiyong Zhao, Wolfgang Sturhahn, E. Ercan Alp, J. Timothy Sage
"Vibrational dynamics of oxygenated heme proteins"
Chem. Commun. 48, (51) 6340-6342 (2012) [PDF] [doi]
194 | Siu Yee New, Nicholas M. Marshall, T. S. Andy Hor, Feng Xue, Yi Lu
"Redox tuning of two biological copper centers through non-covalent interactions: same trend but different magnitude"
Chem. Commun. 48, (35) 4217-4219 (2012) [PDF] [doi]
193 | Panshu Song, Yu Xiang, Hang Xing, Zhaojuan Zhou, Aijun Tong, Yi Lu
"Label-Free Catalytic and Molecular Beacon Containing an Abasic Site for Sensitive Fluorescent Detection of Small Inorganic and Organic Molecules"
Analytical Chemistry 84, 2916-2922 (2012) [PDF] [doi]
192 | Hannah E. Ihms, Yi Lu
"In Vitro Selection of Metal Ion-Selective DNAzymes"
in "Ribozymes", Methods in Molecular Biology, Vol. 848, Jorg S. Hartig, ed.; Humana Press: Hatfield, UK; pp. 297-316 (2012) [doi]
191 | Yu Xiang, Yi Lu
"Using Commercially Available Personal Glucose Meters for Portable Quantification of DNA"
Analytical Chemistry 84, 1975-1980 (2012) [PDF] [doi] [news]
190 | Hui Wei, Yi Lu
"Catalysis of Gold Nanoparticles within Lysozyme Single Crystals"
Chemistry - An Asian Journal 7, 680-683 (2012) [PDF] [doi]
189 | Kevin E. Nelson, Hannah E. Ihms, Debapriya Mazumdar, Peter J. Bruesehoff, Yi Lu
"The Importance of Peripheral Sequences in Determining the Metal Selectivity of an in Vitro-Selected Co2+-Dependent DNAzyme"
ChemBioChem 13, 381-391 (2012) [PDF] [doi]
188 | Hang Xing, Zidong Wang, Zhida Xu, Ngo Yin Wong, Yu Xiang, Gang Logan Liu, Yi Lu
"DNA-Directed Assembly of Asymmetric Nanoclusters Using Janus Nanoparticles"
ACS Nano 6, 802-809 (2012) [PDF] [doi] [news]
187 | Tian Lan, Yi Lu
"Metal Ion-Dependent DNAzymes and Their Applications as Biosensors"
in "Interplay between Metal Ions and Nucleic Acids", Metal Ions in Life Sciences, Vol. 10, Astrid Sigel, Helmut Sigel, Roland K. O. Sigel, eds.; Springer Netherlands; pp. 217-248 (2012) [doi]
2011
186 | Winston A. Anderson, Richard M. Amasino, Manuel Ares Jr., Utpal Banerjee, Bonnie Bartel, Victor G. Corces, Catherine L. Drennan, Sarah C. R. Elgin, Irving R. Epstein, Ellen Fanning, Louis J. Guillette Jr., Jo Handelsman, Graham F. Hatfull, Ronald Raymond Hoy, Darcy Kelley, Leslie A. Leinwand, Richard Losick, Yi Lu, David G. Lynn, Claudia Neuhauser, Diane K. O'Dowd, Toto Olivera, Pavel Pevzner, Rebecca R. Richards-Kortum, Jasper Rine, Robert L. Sah, Scott A. Strobel, Graham C. Walker, David R. Walt, Isiah M. Warner, Sue Wessler, Huntington F. Willard, Richard N. Zare
"Competencies: A Cure for Pre-Med Curriculum"
Science 334, 760-761 (2011) [PDF] [doi]
185 | Tiffany D. Wilson, Masha G. Savelieff, Mark J. Nilges, Nicholas M. Marshall, Yi Lu
"Kinetics of Copper Incorporation into a Biosynthetic Purple CuA Azurin: Characterization of Red, Blue, and a New Intermediate Species"
Journal of the American Chemical Society 133, 20778-20792 (2011) [PDF] [doi]
184 | Dewain K. Garner, Lei Liang, David A. Barrios, Jun-Long Zhang, Yi Lu
"The Important Role of Covalent Anchor Positions in Tuning Catalytic Properties of a Rationally Designed MnSalen-Containing Metalloenzyme"
ACS Catalysis 1, 1083-1089 (2011) [PDF] [doi]
181 | Takahiro Hayashi, Kyle D. Miner, Natasha Yeung, Ying-Wu Lin, Yi Lu, Pierre Moënne-Loccoz
"Spectroscopic Characterization of Mononitrosyl Complexes in Heme–Nonheme Diiron Centers within the Myoglobin Scaffold (FeBMbs): Relevance to Denitrifying NO Reductase"
Biochemistry 50, 5939-5947 (2011) [PDF] [doi]
180 | Ngo Yin Wong, Chuan Zhang, Li Huey Tan, Yi Lu
"Site-Specific Attachment of Proteins onto a 3D DNA Tetrahedron through Backbone-Modified Phosphorothioate DNA"
Small 7, 1427-1430 (2011) [doi]
178 | Hui Wei, Zidong Wang, Jiong Zhang, Stephen House, Yi-Gui Gao, Limin Yang, Howard Robinson, Li Huey Tan, Hang Xing, Changjun Hou, Ian M. Robertson, Jian-Min Zuo, Yi Lu
"Time-dependent, protein-directed growth of gold nanoparticles within a single crystal of lysozyme"
Nature Nanotechnology 6, 93-97 (2011) [PDF] [doi] [news]
177 | Nandini Nagraj, Yi Lu
"Chapter 5 Catalytic Nucleic Acid Biosensors for Environmental Monitoring"
in "Nucleic Acid Biosensors for Environmental Pollution Monitoring", The Royal Society of Chemistry; pp. 82-98 (2011) [doi]
176 | Zhenghao Yang, Chongchong Yan, Yuncong Chen, Chengcheng Zhu, Changli Zhan, Xindian Dong, Weiqi Yang, Zijian Guo, Yi Lu, Weijiang He
"A novel terpyridine/benzofurazan hybrid fluorophore: metal sensing behavior and application"
Dalton Transactions 40, 2173-2176 (2011) [PDF] [doi]
175 | Xiao-Bing Zhang, Rong-Mei Kong, Yi Lu
"Metal Ion Sensors Based on DNAzymes and Related DNA Molecules"
Annual Review of Analytical Chemistry 4, 105-128 (2011) [PDF] [doi]
174 | Steven M Berry, Yi Lu
"Protein Structure Design and Engineering"
in "Encyclopedia of Life Sciences", John Wiley & Sons, Ltd: Chichester, UK; (2011) [doi]
173 | Seyed-Fakhreddin Torabi, Yi Lu
"Small-molecule diagnostics based on functional DNA nanotechnology: a dipstick test for mercury"
Faraday Discuss. 149, (0) 125-135 (2011) [doi]
2010
172 | Kevin M. Clark, Yang Yu, Nicholas M. Marshall, Nathan A. Sieracki, Mark J. Nilges, Ninian J. Blackburn, Wilfred A. van der Donk, Yi Lu
"Transforming a Blue Copper into a Red Copper Protein: Engineering Cysteine and Homocysteine into the Axial Position of Azurin Using Site-Directed Mutagenesis and Expressed Protein Ligation"
Journal of the American Chemical Society 132, 10093-10101 (2010) [PDF] [doi]
171 | Ying-Wu Lin, Natasha Yeung, Yi-Gui Gao, Kyle D. Miner, Lanyu Lei, Howard Robinson, Yi Lu
"Introducing a 2-His-1-Glu Nonheme Iron Center into Myoglobin Confers Nitric Oxide Reductase Activity"
Journal of the American Chemical Society 132, 9970-9972 (2010) [PDF] [doi]
170 | Jung Heon Lee, Ngo Yin Wong, Li Huey Tan, Zidong Wang, Yi Lu
"Controlled Alignment of Multiple Proteins and Nanoparticles with Nanometer Resolution via Backbone-Modified Phosphorothioate DNA and Bifunctional Linkers"
Journal of the American Chemical Society 132, 8906-8908 (2010) [PDF] [doi]
169 | Matthew S. Thorum, Cyrus A. Anderson, Jeremy J. Hatch, Andrew S. Campbell, Nicholas M. Marshall, Steven C. Zimmerman, Yi Lu, Andrew A. Gewirth
"Direct, Electrocatalytic Oxygen Reduction by Laccase on Anthracene-2-methanethiol-Modified Gold"
The Journal of Physical Chemistry Letters 1, 2251-2254 (2010) [PDF] [doi]
168 | Jung Heon Lee, Mehmet V. Yigit, Debapriya Mazumdar, Yi Lu
"Molecular diagnostic and drug delivery agents based on aptamer-nanomaterial conjugates"
Advanced Drug Delivery Reviews 62, 592-605 (2010) [doi]
167 | Jinli Zhang, Lin Zheng, Xian Wang, Ying Xiao, Yi Lu, Wei Li
"Branched silica nanostructures oriented by dynamic G-quadruplex transformation"
Materials Research Bulletin 45, 1954-1959 (2010) [doi]
166 | Xiao-Bing Zhang, Zidong Wang, Hang Xing, Yu Xiang, Yi Lu
"Catalytic and Molecular Beacons for Amplified Detection of Metal Ions and Organic Molecules with High Sensitivity"
Analytical Chemistry 82, 5005-5011 (2010) [PDF] [doi]
165 | Tian Lan, Kimberly Furuya, Yi Lu
"A highly selective lead sensor based on a classic lead DNAzyme"
Chemical Communications 46, 3896-3898 (2010) [doi]
164 | Zidong Wang, Jieqian Zhang, Jonathan M. Ekman, Paul J. A. Kenis, Yi Lu
"DNA-Mediated Control of Metal Nanoparticle Shape: One-Pot Synthesis and Cellular Uptake of Highly Stable and Functional Gold Nanoflowers"
Nano Letters 10, 1886-1891 (2010) [PDF] [doi]
163 | Hui Wei, Zidong Wang, Limin Yang, Shiliang Tian, Changjun Hou, Yi Lu
"Lysozyme-stabilized gold fluorescent cluster: Synthesis and application as Hg2+ sensor"
The Analyst 135, 1406-1410 (2010) [doi]
162 | Masha Savelieff, Yi Lu
"CuA centers and their biosynthetic models in azurin"
Journal of Biological Inorganic Chemistry 15, 461-483 (2010) [doi]
161 | Ying-Wu Lin, Natasha Yeung, Yi-Gui Gao, Kyle D. Miner, Shiliang Tian, Howard Robinson, Yi Lu
"Roles of glutamates and metal ions in a rationally designed nitric oxide reductase based on myoglobin"
Proceedings of the National Academy of Sciences 107, 8581-8586 (2010) [PDF] [doi]
160 | Yu Xiang, Zidong Wang, Hang Xing, Ngo Yin Wong, Yi Lu
"Label-Free Fluorescent Functional DNA Sensors Using Unmodified DNA: A Vacant Site Approach"
Analytical Chemistry 82, 4122-4129 (2010) [PDF] [doi]
159 | Yi Lu
"Metal ions as matchmakers for proteins"
Proceedings of the National Academy of Sciences 107, 1811-1812 (2010) [PDF] [doi]
158 | Weichen Xu, Yi Lu
"Label-Free Fluorescent Aptamer Sensor Based on Regulation of Malachite Green Fluorescence"
Analytical Chemistry 82, 574-578 (2010) [PDF] [doi]
157 | Changyuan Lu, Xuan Zhao, Yi Lu, Denis L. Rousseau, Syun-Ru Yeh
"Role of Copper Ion in Regulating Ligand Binding in a Myoglobin-Based Cytochrome c Oxidase Model"
Journal of the American Chemical Society 132, 1598-1605 (2010) [PDF] [doi]
156 | Debapriya Mazumdar, Juewen Liu, Geng Lu, Juanzuo Zhou, Yi Lu
"Easy-to-use dipstick tests for detection of lead in paints using non-cross-linked gold nanoparticle-DNAzyme conjugates"
Chemical Communications 46, 1416-1418 (2010) [doi] [news]
155 | Eric L. Null, Yi Lu
"Rapid determination of enantiomeric ratio using fluorescent DNA or RNA aptamers"
The Analyst 135, 419-422 (2010) [doi]
2009
153 | Natasha Yeung, Ying-Wu Lin, Yi-Gui Gao, Xuan Zhao, Brandy S. Russell, Lanyu Lei, Kyle D. Miner, Howard Robinson, Yi Lu
"Rational design of a structural and functional nitric oxide reductase"
Nature 462, 1079-1082 (2009) [doi] [news]
152 | Nicholas M. Marshall, Dewain K. Garner, Tiffany D. Wilson, Yi-Gui Gao, Howard Robinson, Mark J. Nilges, Yi Lu
"Rationally tuning the reduction potential of a single cupredoxin beyond the natural range"
Nature 462, 113-116 (2009) [doi] [news]
151 | Mehmet Veysel Yigit, Abhijit Mishra, Rong Tong, Jianjun Cheng, Gerard C.L. Wong, Yi Lu
"Inorganic Mercury Detection and Controlled Release of Chelating Agents from Ion-Responsive Liposomes"
Chemistry & Biology 16, 937-942 (2009) [doi]
150 | Yi Lu, Natasha Yeung, Nathan Sieracki, Nicholas M. Marshall
"Design of functional metalloproteins"
Nature 460, 855-862 (2009) [doi]
149 | Zhengyi Wu, Qin Liu, Xiao Liang, Xiaoliang Yang, Ningyan Wang, Xinghao Wang, Hongzhe Sun, Yi Lu, Zijian Guo
"Reactivity of platinum-based antitumor drugs towards a Met- and His-rich 20mer peptide corresponding to the N-terminal domain of human copper transporter 1"
Journal of Biological Inorganic Chemistry 14, 1313-1323 (2009) [doi]
148 | Zehui Cao, Rong Tong, Abhijit Mishra, Weichen Xu, Gerard C L Wong, Jianjun Cheng, Yi Lu
"Reversible Cell-Specific Drug Delivery with Aptamer-Functionalized Liposomes"
Angewandte Chemie International Edition 48, 6494-6498 (2009) [doi] [news]
147 | Nandini Nagraj, Juewen Liu, Stephanie Sterling, Jenny Wu, Yi Lu
"DNAzyme catalytic beacon sensors that resist temperature-dependent variations"
Chemical Communications 2009, 4103-4105 (2009) [doi]
146 | Juewen Liu, Zehui Cao, Yi Lu
"Functional Nucleic Acid Sensors"
Chemical Reviews 109, 1948-1998 (2009) [doi]
145 | Jianhui Zhu, Miaoxin Lin, Damin Fan, Ziyi Wu, Yuncong Chen, Junfeng Zhang, Yi Lu, Zijian Guo
"The role of bridging ligands in determining DNA-binding ability and cross-linking patterns of dinuclear platinum(ii) antitumour complexes"
Dalton Transactions 2009, 10889-10895 (2009) [doi]
144 | Debapriya Mazumdar, Nandini Nagraj, Hee-Kyung Kim, Xiangli Meng, Andrea K. Brown, Qian Sun, Wei Li, Yi Lu
"Activity, Folding and Z-DNA Formation of the 8-17 DNAzyme in the Presence of Monovalent Ions"
Journal of the American Chemical Society 131, 5506-5515 (2009) [PDF] [doi]
143 | Jun-Long Zhang, Dewain K Garner, Lei Liang, David A Barrios, Yi Lu
"Noncovalent Modulation of pH-Dependent Reactivity of a Mn-Salen Cofactor in Myoglobin with Hydrogen Peroxide"
Chemistry - A European Journal 15, 7481-7489 (2009) [doi]
142 | Danqun Huo, Limin Yang, Changjun Hou, Huanbao Fa, Xiaogang Luo, Yi Lu, Xiaolin Zheng, Jun Yang, Li Yang
"Molecular interactions of monosulfonate tetraphenylporphyrin (TPPS1) and meso-tetra(4-sulfonatophenyl)porphyrin (TPPS) with dimethyl methylphosphonate (DMMP)"
Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 74, 336-343 (2009) [doi]
141 | Kevin M. Clark, Wilfred A. van der Donk, Yi Lu
"Chapter 5 Expressed Protein Ligation for Metalloprotein Design and Engineering"
in "Non-Natural Amino Acids", Methods in Enzymology, Vol. 462, Tom W. Muir, John N. Abelson, eds.; Academic Press; pp. 97-115 (2009) [doi]
140 | Jianhui Zhu, Yongmei Zhao, Yanyan Zhu, Ziyi Wu, Miaoxin Lin, Weijiang He, Yan Wang, Guangju Chen, Lei Dong, Junfeng Zhang, Yi Lu, Zijian Guo
"DNA Cross-Linking Patterns Induced by an Antitumor-Active Trinuclear Platinum Complex and Comparison with Its Dinuclear Analogue"
Chemistry - A European Journal 15, 5245-5253 (2009) [doi]
139 | B. Ravel, S.C. Slimmer, X. Meng, G.C.L. Wong, Y. Lu
"EXAFS studies of catalytic DNA sensors for mercury contamination of water"
Radiation Physics and Chemistry 78, S75-S79 (2009) [doi]
138 | Yi Lu, Juewen Liu, Debapriya Mazumdar
"Nanoparticles/Dip Stick"
in "Nucleic Acid and Peptide Aptamers: Methods and Protocols", Methods in Molecular Biology, Vol. 535, Gunter Mayer, ed.; pp. 223-239 (2009) [doi]
137 | Zidong Wang, Yi Lu
"Functional DNA directed assembly of nanomaterials for biosensing"
J. Mater. Chem. 19, (13) 1788-1798 (2009) [doi] [news]
136 | Zehui Cao, Yi Lu
"New Metallo-DNAzymes: Fundamental Studies of Metal-DNA Interactions and Metal Sensing Applications"
in "Metal Complex-DNA Interactions", Nick Hadjiliadis, Einar Sletten, eds.; Wiley-Blackwell: Oxford, UK; pp. 395-414 (2009) [doi]
135 | Yingfu Li, Yi Lu
"Functional Nucleic Acids for Sensing and Other Analytical Applications"
Integrated Analytical Systems, Springer: New York, NY; (2009) [doi]
134 | Juewen Liu, Yi Lu
"Colorimetric and Fluorescent Biosensors Based on Directed Assembly of Nanomaterials with Functional DNA"
in "Functional Nucleic Acids for Analytical Applications", Integrated Analytical Systems, Yingfu Li, Yi Lu, eds.; Springer: New York, NY; pp. 155-178 (2009) [doi]
133 | Andrea K. Brown, Juewen Liu, Ying He, Yi Lu
"Biochemical Characterization of a Uranyl Ion-Specific DNAzyme"
ChemBioChem 10, 486-492 (2009) [doi]
2008
132 | Jang-Ung Park, Jung Heon Lee, Ungyu Paik, Yi Lu, John A. Rogers
"Nanoscale Patterns of Oligonucleotides Formed by Electrohydrodynamic Jet Printing with Applications in Biosensing and Nanomaterials Assembly"
Nano Letters 8, 4210-4216 (2008) [PDF] [doi]
131 | Zidong Wang, Jung Heon Lee, Yi Lu
"Highly sensitive "turn-on" fluorescent sensor for Hg2+ in aqueous solution based on structure-switching DNA"
Chemical Communications 2008, 6005-6007 (2008) [doi]
130 | Masha G. Savelieff, Tiffany D. Wilson, Youssef Elias, Mark J. Nilges, Dewain K. Garner, Yi Lu
"Experimental evidence for a link among cupredoxins: Red, blue, and purple copper transformations in nitrous oxide reductase"
Proceedings of the National Academy of Sciences 105, 7919-7924 (2008) [PDF] [doi] [news]
129 | Jung Heon Lee, Zidong Wang, Juewen Liu, Yi Lu
"Highly Sensitive and Selective Colorimetric Sensors for Uranyl (UO22+): Development and Comparison of Labeled and Label-Free DNAzyme-Gold Nanoparticle Systems"
Journal of the American Chemical Society 130, 14217-14226 (2008) [PDF] [doi]
127 | Hee-Kyung Kim, Jing Li, Nandini Nagraj, Yi Lu
"Probing Metal Binding in the 8-17 DNAzyme by TbIII Luminescence Spectroscopy"
Chemistry - A European Journal 14, 8696-8703 (2008) [doi]
126 | Yi Lu, Juewen Liu
"Catalyst-functionalized nanomaterials"
Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology 1, 35-46 (2008) [doi]
125 | Debapriya Mazumdar, Juewen Liu, Yi Lu
"Functional Nucleic Acid-Directed Assembly of Nanomaterials and their Applications as Colorimetric and Fluorescent Sensors for Trace Contaminants in Water"
in "Nanotechnology Applications for Clean Water", Nora Savage, Mamadou Diallo, Jeremiah Duncan, Anita Street, Richard Sustich, eds.; pp. 427-446 (2008) [doi]
123 | Margaret H. S. Shyr, Daryl P. Wernette, Pierre Wiltzius, Yi Lu, Paul V. Braun
"DNA and DNAzyme-Mediated 2D Colloidal Assembly"
Journal of the American Chemical Society 130, 8234-8240 (2008) [PDF] [doi]
122 | Tulika S. Dalavoy, Daryl P. Wernette, Maojun Gong, Jonathan V. Sweedler, Yi Lu, Bruce R. Flachsbart, Mark A. Shannon, Paul W. Bohn, Donald M. Cropek
"Immobilization of DNAzyme catalytic beacons on PMMA for Pb2+ detection"
Lab on a Chip 8, 786-793 (2008) [doi]
121 | Xiangjin Xie, Serge I. Gorelsky, Ritimukta Sarangi, Dewain K. Garner, Hee Jung Hwang, Keith O. Hodgson, Britt Hedman, Yi Lu, Edward I. Solomon
"Perturbations to the Geometric and Electronic Structure of the CuA Site: Factors that Influence Delocalization and Their Contributions to Electron Transfer"
Journal of the American Chemical Society 130, 5194-5205 (2008) [PDF] [doi]
120 | Yi Lu, Dewain K. Garner, Jun-long Zhang, Tadhg P. Begley
"Artificial Metalloproteins: Design and Engineering"
in "Wiley Encyclopedia of Chemical Biology", John Wiley & Sons, Inc.; (2008) [doi]
119 | Jun-Long Zhang, Dewain K. Garner, Lei Liang, Qian Chen, Yi Lu
"Protein scaffold of a designed metalloenzyme enhances the chemoselectivity in sulfoxidation of thioanisole"
Chemical Communications , 1665-1667 (2008) [doi]
118 | Ritimukta Sarangi, Serge I. Gorelsky, Lipika Basumallick, Hee Jung Hwang, Russell C. Pratt, T. Daniel P. Stack, Yi Lu, Keith O. Hodgson, Britt Hedman, Edward I. Solomon
"Spectroscopic and Density Functional Theory Studies of the Blue−Copper Site in M121SeM and C112SeC Azurin: Cu−Se Versus Cu−S Bonding"
Journal of the American Chemical Society 130, 3866-3877 (2008) [PDF] [doi]
117 | Masha G. Savelieff, Yi Lu
"pH dependent copper binding properties of a CuA azurin variant with both bridging cysteines replaced with serines"
Inorganica Chimica Acta 361, 1087-1094 (2008) [doi]
116 | Daryl P. Wernette, Juewen Liu, Paul W. Bohn, Yi Lu
"Functional DNA-Based Nanoscale Materials and Devices for Sensing Trace Contaminants in Water"
MRS Bulletin 33, 34-41 (2008) [PDF]
115 | Mehmet Veysel Yigit, Debapriya Mazumdar, Yi Lu
"MRI Detection of Thrombin with Aptamer Functionalized Superparamagnetic Iron Oxide Nanoparticles"
Bioconjugate Chemistry 19, 412-417 (2008) [PDF] [doi] [news]
114 | Nathan A. Sieracki, Hee Jung Hwang, Michelle K. Lee, Dewain K. Garner, Yi Lu
"A temperature independent pH (TIP) buffer for biomedical biophysical applications at low temperatures"
Chemical Communications , 823-825 (2008) [doi] [news]
2007
113 | Lauren A. Denofrio, Brandy Russell, David Lopatto, Yi Lu
"Linking Student Interests to Science Curricula"
Science 318, 1872-1873 (2007) [PDF] [doi] [news]
112 | Hee-Kyung Kim, Ivan Rasnik, Juewen Liu, Taekjip Ha, Yi Lu
"Dissecting metal ion-dependent folding and catalysis of a single DNAzyme"
Nat Chem Biol 3, 763-768 (2007) [doi] [news]
111 | Juewen Liu, Yi Lu
"Colorimetric Cu2+ detection with a ligation DNAzyme and nanoparticles"
Chemical Communications , 4872-4874 (2007) [doi] [news]
110 | Jung Heon Lee, Daryl P. Wernette, Mehmet V. Yigit, Juewen Liu, Zidong Wang, Yi Lu
"Site-Specific Control of Distances between Gold Nanoparticles Using Phosphorothioate Anchors on DNA and a Short Bifunctional Molecular Fastener"
Angewandte Chemie International Edition 46, 9006-9010 (2007) [doi]
109 | Juewen Liu, Yi Lu
"Rational Design of "Turn-On" Allosteric DNAzyme Catalytic Beacons for Aqueous Mercury Ions with Ultrahigh Sensitivity and Selectivity"
Angewandte Chemie International Edition 46, 7587-7590 (2007) [doi]
108 | Mehmet Veysel Yigit, Debapriya Mazumdar, Hee-Kyung Kim, Jung Heon Lee, Boris Odintsov, Yi Lu
"Smart "Turn-on" Magnetic Resonance Contrast Agents Based on Aptamer-Functionalized Superparamagnetic Iron Oxide Nanoparticles"
ChemBioChem 8, 1675-1678 (2007) [doi]
107 | Juewen Liu, Yi Lu
"A DNAzyme Catalytic Beacon Sensor for Paramagnetic Cu2+ Ions in Aqueous Solution with High Sensitivity and Selectivity"
Journal of the American Chemical Society 129, 9838-9839 (2007) [PDF] [doi]
106 | Daryl P. Wernette, Carolyn Mead, Paul W. Bohn, Yi Lu
"Surface Immobilization of Catalytic Beacons Based on Ratiometric Fluorescent DNAzyme Sensors: A Systematic Study"
Langmuir 23, 9513-9521 (2007) [PDF] [doi]
105 | Juewen Liu, Yi Lu
"Non-Base Pairing DNA Provides a New Dimension for Controlling Aptamer-Linked Nanoparticles and Sensors"
Journal of the American Chemical Society 129, 8634-8643 (2007) [PDF] [doi]
104 | Hee-Kyung Kim, Juewen Liu, Jing Li, Nandini Nagraj, Mingxi Li, Caroline M.-B. Pavot, Yi Lu
"Metal-Dependent Global Folding and Activity of the 8-17 DNAzyme Studied by Fluorescence Resonance Energy Transfer"
Journal of the American Chemical Society 129, 6896-6902 (2007) [PDF] [doi]
103 | Juewen Liu, Jung Heon Lee, Yi Lu
"Quantum Dot Encoding of Aptamer-Linked Nanostructures for One-Pot Simultaneous Detection of Multiple Analytes"
Analytical Chemistry 79, 4120-4125 (2007) [PDF] [doi] [news]
102 | Juewen Liu, Andrea K. Brown, Xiangli Meng, Donald M. Cropek, Jonathan D. Istok, David B. Watson, Yi Lu
"A catalytic beacon sensor for uranium with parts-per-trillion sensitivity and millionfold selectivity"
Proceedings of the National Academy of Sciences 104, 2056-2061 (2007) [PDF] [doi] [news]
101 | Ole Farver, Hee Jung Hwang, Yi Lu, Israel Pecht
"Reorganization Energy of the CuA Center in Purple Azurin: Impact of the Mixed Valence-to-Trapped Valence State Transition"
The Journal of Physical Chemistry B 111, 6690-6694 (2007) [PDF] [doi]
99 | Yi Lu, Thomas D. Pfister
"Beyond Heme‐Thiolate Interactions: Roles of the Secondary Coordination Sphere in Cytochrome P450 Systems"
in "Metal Ions in Life Sciences", Vol. 3, Astrid Sigel, Helmut Sigel, Roland K. O. Sigel, eds.; John Wiley & Sons, Ltd: Chichester, UK; pp. 267-284 (2007) [doi]
98 | Thomas Pfister, Amir Mirarefi, Alan Gengenbach, Xuan Zhao, Connor Danstrom, Nicole Conatser, Yi-Gui Gao, Howard Robinson, Charles Zukoski, Andrew Wang, Yi Lu
"Kinetic and crystallographic studies of a redesigned manganese-binding site in cytochrome c peroxidase"
Journal of Biological Inorganic Chemistry 12, 126-137 (2007) [doi]
2006
97 | Yi Lu, Juewen Liu
"Functional DNA nanotechnology: emerging applications of DNAzymes and aptamers"
Current Opinion in Biotechnology 17, 580-588 (2006) [doi]
96 | Dewain K. Garner, Mark D. Vaughan, Hee Jung Hwang, Masha G. Savelieff, Steven M. Berry, John F. Honek, Yi Lu
"Reduction Potential Tuning of the Blue Copper Center in Pseudomonas aeruginosa Azurin by the Axial Methionine as Probed by Unnatural Amino Acids"
Journal of the American Chemical Society 128, 15608-15617 (2006) [PDF] [doi]
95 | Juewen Liu, Debapriya Mazumdar, Yi Lu
"A Simple and Sensitive 'Dipstick' Test in Serum Based on Lateral Flow Separation of Aptamer-Linked Nanostructures"
Angewandte Chemie International Edition 45, 7955-7959 (2006) [doi] [news]
93 | Yi Lu
"Metalloprotein Design & Engineering"
in "Encyclopedia of Inorganic Chemistry", Vol. V, R. Bruce King, ed.; John Wiley & Sons, Ltd: Chichester, UK; pp. 3159-3192 (2006) [doi]
91 | Yi Lu
"Biosynthetic Inorganic Chemistry"
Angewandte Chemie International Edition 45, 5588-5601 (2006) [doi]
90 | Juewen Liu, Yi Lu
"Design of asymmetric DNAzymes for dynamic control of nanoparticle aggregation states in response to chemical stimuli"
Organic & Biomolecular Chemistry 4, 3435-3441 (2006) [doi]
89 | J. Liu, Y. Lu
"Smart Nanomaterials Responsive to Multiple Chemical Stimuli with Controllable Cooperativity"
Advanced Materials 18, 1667-1671 (2006) [doi] [news]
88 | Xuan Zhao, Natasha Yeung, Brandy S. Russell, Dewain K. Garner, Yi Lu
"Catalytic Reduction of NO to N2O by a Designed Heme Copper Center in Myoglobin: Implications for the Role of Metal Ions"
Journal of the American Chemical Society 128, 6766-6767 (2006) [PDF] [doi]
87 | Juewen Liu, Yi Lu
"Fast Colorimetric Sensing of Adenosine and Cocaine Based on a General Sensor Design Involving Aptamers and Nanoparticles"
Angewandte Chemie International Edition 45, 90-94 (2006) [doi] [news]
86 | Lu Yi
"Catalytic Nucleic Acids (Ribozymes and Deoxyribozymes)"
in "Biological Inorganic Chemistry: Structure & Reactivity", Ivano Bertini, Harry B. Gray, Joan S. Valentine, eds.; University Science Books, Inc.: Mill Valley, CA.; pp. 215-228 (2006)
85 | Juewen Liu, Yi Lu
"Fluorescent DNAzyme Biosensors for Metal Ions Based on Catalytic Molecular Beacons"
Methods in Molecular Biology 335, (Methods in Molecular Biology) 275-288 (2006) [doi]
84 | Juewen Liu, Yi Lu
"Multi-Fluorophore Fluorescence Resonance Energy Transfer for Probing Nucleic Acids Structure and Folding"
Methods in Molecular Biology 335, (Methods in Molecular Biology) 257-271 (2006) [doi]
83 | Hee Jung Hwang, Nandini Nagraj, Yi Lu
"Spectroscopic Characterizations of Bridging Cysteine Ligand Variants of an Engineered Cu2(SCys)2 CuA Azurin"
Inorganic Chemistry 45, 102-107 (2006) [PDF] [doi]
82 | Daryl P. Wernette, Carla B. Swearingen, Donald M. Cropek, Yi Lu, Jonathan V. Sweedler, Paul W. Bohn
"Incorporation of a DNAzyme into Au-coated nanocapillary array membranes with an internal standard for Pb(ii) sensing"
The Analyst 131, 41-47 (2006) [doi]
2005
81 | Ningyan Wang, Xuan Zhao, Yi Lu
"Role of Heme Types in Heme-Copper Oxidases: Effects of Replacing a Heme b with a Heme o Mimic in an Engineered Heme-Copper Center in Myoglobin"
Journal of the American Chemical Society 127, 16541-16547 (2005) [PDF] [doi]
80 | Hee Jung Hwang, James R. Carey, Evan T. Brower, Alan J. Gengenbach, Joseph A. Abramite, Yi Lu
"Blue Ferrocenium Azurin: An Organometalloprotein with Tunable Redox Properties"
Journal of the American Chemical Society 127, 15356-15357 (2005) [PDF] [doi]
79 | Juewen Liu, Yi Lu
"Stimuli-Responsive Disassembly of Nanoparticle Aggregates for Light-Up Colorimetric Sensing"
Journal of the American Chemical Society 127, 12677-12683 (2005) [PDF] [doi]
78 | Tae-Jin Yim, Juewen Liu, Yi Lu, Ravi S. Kane, Jonathan S. Dordick
"Highly Active and Stable DNAzyme-Carbon Nanotube Hybrids"
Journal of the American Chemical Society 127, 12200-12201 (2005) [PDF] [doi]
77 | Juewen Liu, Daryl P. Wernette, Yi Lu
"Proofreading and Error Removal in a Nanomaterial Assembly"
Angewandte Chemie International Edition 44, 7290-7293 (2005) [PDF] [doi]
76 | Haiying Wei, Xiaoyong Wang, Qin Liu, Yuhua Mei, Yi Lu, Zijian Guo
"Disulfide Bond Cleavage Induced by a Platinum(II) Methionine Complex"
Inorganic Chemistry 44, 6077-6081 (2005) [PDF] [doi]
75 | In-Hyoung Chang, Joseph J. Tulock, Juewen Liu, Won-Suk Kim, Donald M. Cannon, Yi Lu, Paul W. Bohn, Jonathan V. Sweedler, Donald M. Cropek
"Miniaturized Lead Sensor Based on Lead-Specific DNAzyme in a Nanocapillary Interconnected Microfluidic Device"
Environmental Science & Technology 39, 3756-3761 (2005) [PDF] [doi]
74 | Kevin E. Nelson, Peter J. Bruesehoff, Yi Lu
"In Vitro Selection of High Temperature Zn2+-Dependent DNAzymes"
Journal of Molecular Evolution 61, 216-225 (2005) [PDF] [doi]
73 | Hee Jung Hwang, Steven M. Berry, Mark J. Nilges, Yi Lu
"Axial Methionine Has Much Less Influence on Reduction Potentials in a CuA Center than in a Blue Copper Center"
Journal of the American Chemical Society 127, 7274-7275 (2005) [PDF] [doi]
72 | Lu Yi, Steven M. Berry
"Protein Structure Design and Engineering"
in "Encyclopedia of Life Sciences", John Wiley & Sons, Ltd.: Chichester, UK; (2005) [PDF] [doi]
70 | Kashan A. Shaikh, Kee Suk Ryu, Edgar D. Goluch, Jwa-Min Nam, Juewen Liu, C. Shad Thaxton, Thomas N. Chiesl, Annelise E. Barron, Yi Lu, Chad A. Mirkin, Chang Liu
"A modular microfluidic architecture for integrated biochemical analysis"
Proceedings of the National Academy of Sciences of the United States of America 102, 9745-9750 (2005) [PDF] [doi]
69 | Jingwen Chen, Xiaoyong Wang, Yangguang Zhu, Jun Lin, Xiaoliang Yang, Yizhi Li, Yi Lu, Zijian Guo
"An Asymmetric Dizinc Phosphodiesterase Model with Phenolate and Carboxylate Bridges"
Inorganic Chemistry 44, 3422-3430 (2005) [PDF] [doi]
68 | Jennifer L. Seifert, Thomas D. Pfister, Judith M. Nocek, Yi Lu, Brian M. Hoffman
"Hopping in the Electron-Transfer Photocycle of the 1:1 Complex of Zn-Cytochrome c Peroxidase with Cytochrome c"
Journal of the American Chemical Society 127, 5750-5751 (2005) [PDF] [doi]
66 | Thomas D. Pfister, Takahiro Ohki, Takafumi Ueno, Isao Hara, Seiji Adachi, Yumiko Makino, Norikazu Ueyama, Yi Lu, Yoshihito Watanabe
"Monooxygenation of an Aromatic Ring by F43W/H64D/V68I Myoglobin Mutant and Hydrogen Peroxide"
Journal of Biological Chemistry 280, 12858-12866 (2005) [PDF] [doi]
64 | Carla B. Swearingen, Daryl P. Wernette, Donald M. Cropek, Yi Lu, Jonathan V. Sweedler, Paul W. Bohn
"Immobilization of a Catalytic DNA Molecular Beacon on Au for Pb(II) Detection"
Analytical Chemistry 77, 442-448 (2005) [PDF] [doi]
2004
63 | Juewen Liu, Yi Lu
"Accelerated Color Change of Gold Nanoparticles Assembled by DNAzymes for Simple and Fast Colorimetric Pb2+ Detection"
Journal of the American Chemical Society 126, 12298-12305 (2004) [PDF] [doi]
62 | Hee Jung Hwang, Yi Lu
"pH-dependent transition between delocalized and trapped valence states of a CuA center and its possible role in proton-coupled electron transfer"
Proceedings of the National Academy of Sciences of the United States of America 101, 12842-12847 (2004) [PDF] [doi]
60 | James R. Carey, Steven K. Ma, Thomas D. Pfister, Dewain K. Garner, Hyeon K. Kim, Joseph A. Abramite, Zhilin Wang, Zijian Guo, Yi Lu
"A Site-Selective Dual Anchoring Strategy for Artificial Metalloprotein Design"
Journal of the American Chemical Society 126, 10812-10813 (2004) [PDF] [doi]
59 | Juewen Liu, Yi Lu
"Colorimetric Biosensors Based on DNAzyme-Assembled Gold Nanoparticles"
Journal of Fluorescence 14, 343-354 (2004) [PDF] [doi]
58 | HeeJung Hwang, Majorie Ang, Yi Lu
"Determination of reduction potential of an engineered Cu A azurin by cyclic voltammetry and spectrochemical titrations"
Journal of Biological Inorganic Chemistry 9, 489-494 (2004) [PDF] [doi]
57 | Martina Ralle, Steven M. Berry, Mark J. Nilges, Matt D. Gieselman, Wilfred A. van der Donk, Yi Lu, Ninian J. Blackburn
"The Selenocysteine-Substituted Blue Copper Center: Spectroscopic Investigations of Cys112SeCys Pseudomonas aeruginosa Azurin"
Journal of the American Chemical Society 126, 7244-7256 (2004) [PDF] [doi]
55 | Hee Jung Hwang, Yi Lu
"Spectroscopic evidence for interactions between hexacyanoiron(II/III) and an engineered purple CuA azurin"
Journal of Inorganic Biochemistry 98, 797 - 802 (2004) [PDF] [doi]
2003
54 | Juewen Liu, Yi Lu
"Improving Fluorescent DNAzyme Biosensors by Combining Inter- and Intramolecular Quenchers"
Analytical Chemistry 75, 6666-6672 (2003) [PDF] [doi]
53 | Steven M. Berry, Martina Ralle, Donald W. Low, Ninian J. Blackburn, Yi Lu
"Probing the Role of Axial Methionine in the Blue Copper Center of Azurin with Unnatural Amino Acids"
Journal of the American Chemical Society 125, 8760-8768 (2003) [PDF] [doi]
52 | Juewen Liu, Yi Lu
"A Colorimetric Lead Biosensor Using DNAzyme-Directed Assembly of Gold Nanoparticles"
Journal of the American Chemical Society 125, 6642-6643 (2003) [PDF] [doi] [news]
51 | Andrea K. Brown, Jing Li, Caroline M.-B. Pavot, Yi Lu
"A Lead-Dependent DNAzyme with a Two-Step Mechanism"
Biochemistry 42, 7152-7161 (2003) [PDF] [doi]
50 | Y. Lu
"Electron Transfer: Cupredoxins"
in "Comprehensive Coordination Chemistry II", Vol. 8, J. A. McCleverty, T. J. Meyer, eds.; Pergamon: Oxford; pp. 91-122 (2003) [PDF] [doi]
49 | Manliang Feng, Hiroyasu Tachikawa, Xiaotang Wang, Thomas Pfister, Alan Gengenbach, Yi Lu
"Resonance Raman spectroscopy of cytochrome c peroxidase variants that mimic manganese peroxidase"
Journal of Biological Inorganic Chemistry 8, 699-706 (2003) [PDF] [doi]
48 | Jeffrey A. Sigman, Hyeon K. Kim, Xuan Zhao, James R. Carey, Yi Lu
"The role of copper and protons in heme-copper oxidases: Kinetic study of an engineered heme-copper center in myoglobin"
Proceedings of the National Academy of Sciences of the United States of America 100, 3629-3634 (2003) [PDF] [doi]
47 | Roshan Perera, Masanori Sono, Jeffrey A. Sigman, Thomas D. Pfister, Yi Lu, John H. Dawson
"Neutral thiol as a proximal ligand to ferrous heme iron: Implications for heme proteins that lose cysteine thiolate ligation on reduction"
Proceedings of the National Academy of Sciences of the United States of America 100, 3641-3646 (2003) [PDF] [doi]
46 | Yi Lu, Juewen Liu, Jing Li, Peter J. Bruesehoff, Caroline M. -B. Pavot, Andrea K. Brown
"New highly sensitive and selective catalytic DNA biosensors for metal ions"
Biosensors and Bioelectronics 18, 529 - 540 (2003) [PDF] [doi]
2002
45 | Juewen Liu, Yi Lu
"FRET Study of a Trifluorophore-Labeled DNAzyme"
Journal of the American Chemical Society 124, 15208-15216 (2002) [PDF] [doi]
44 | Geoffrey A. Holloway, Caroline Pavot, Stephen A. Scaringe, Yi Lu, Thomas B. Rauchfuss
"3.0.CO;2-9">An Organometallic Route to Oligonucleotides Containing Phosphoroselenoate"
ChemBioChem 3, 1061-1065 (2002) [PDF] [3.0.CO;2-9">doi]
43 | Boris Epel, Claire S. Slutter, Frank Neese, Peter M. H. Kroneck, Walter G. Zumft, Israel Pecht, Ole Farver, Yi Lu, Daniella Goldfarb
"Electron-Mediating CuA Centers in Proteins: A Comparative High Field 1H ENDOR Study"
Journal of the American Chemical Society 124, 8152-8162 (2002) [PDF] [doi]
42 | Dmitriy Lukoyanov, Steven M. Berry, Yi Lu, William E. Antholine, Charles P. Scholes
"Role of the Coordinating Histidine in Altering the Mixed Valency of CuA: An Electron Nuclear Double Resonance-Electron Paramagnetic Resonance Investigation"
Biophysical Journal 82, 2758-2766 (2002) [PDF] [doi]
40 | Steven M. Berry, Matt D. Gieselman, Mark J. Nilges, Wilfred A. van der Donk, Yi Lu
"An Engineered Azurin Variant Containing a Selenocysteine Copper Ligand"
Journal of the American Chemical Society 124, 2084-2085 (2002) [PDF] [doi]
39 | Bruesehoff P.J., Li J., Augustine III A.J., Lu Y.
"Improving Metal Ion Specificity During In Vitro Selection of Catalytic DNA"
Combinatorial Chemistry & High Throughput Screening 5, 327-335 (2002) [doi]
2001
38 | Thomas D. Pfister, Alan J. Gengenbach, Sung Syn, Yi Lu
"The Role of Redox-Active Amino Acids on Compound I Stability, Substrate Oxidation, and Protein Cross-Linking in Yeast Cytochrome c Peroxidase"
Biochemistry 40, 14942-14951 (2001) [PDF] [doi]
37 | Yi Lu, Steven M. Berry, Thomas D. Pfister
"Engineering Novel Metalloproteins: Design of Metal-Binding Sites into Native Protein Scaffolds"
Chemical Reviews 101, 3047-3080 (2001) [PDF] [doi]
36 | Yi Lu
"What's in a Name"
Chemical and Engineering News 79, (13) 241 (2001) [PDF] [news]
35 | Jeffrey A. Sigman, Xiaotang Wang, Yi Lu
"Coupled Oxidation of Heme by Myoglobin Is Mediated by Exogenous Peroxide"
Journal of the American Chemical Society 123, 6945-6946 (2001) [PDF] [doi]
34 | Serena DeBeer George, Markus Metz, Robert K. Szilagyi, Hongxin Wang, Stephen P. Cramer, Yi Lu, William B. Tolman, Britt Hedman, Keith O. Hodgson, Edward I. Solomon
"A Quantitative Description of the Ground-State Wave Function of CuA by X-ray Absorption Spectroscopy: Comparison to Plastocyanin and Relevance to Electron Transfer"
Journal of the American Chemical Society 123, 5757-5767 (2001) [PDF] [doi]
33 | Paola Turano, Yi Lu
"Iron in Heme and Related Proteins"
in "Handbook on Metalloproteins", Ivano Bertini, Helmut Sigel, Astrid Sigel, eds.; Marcel Dekker, Inc.; pp. 269-356 (2001)
32 | Gengenbach Alan, Wang Xiaotang, Lu Yi
"Designing a Manganese Peroxidase"
in "Oxidative Delignification Chemistry", ACS Symposium Series, Vol. 785, Dimitris S. Argyropoulos, ed.; ACS: Washington, D.C.; pp. 487-500 (2001) [PDF] [doi]
2000
31 | Jing Li, Yi Lu
"A Highly Sensitive and Selective Catalytic DNA Biosensor for Lead Ions"
Journal of the American Chemical Society 122, 10466-10467 (2000) [PDF] [doi] [news]
30 | Michael T. Hay, Yi Lu
"Metal-binding properties of an engineered purple CuA center in azurin"
Journal of Biological Inorganic Chemistry 5, 699-712 (2000) [PDF] [doi]
29 | Jeffrey A. Sigman, Brian C. Kwok, Yi Lu
"From Myoglobin to Heme-Copper Oxidase: Design and Engineering of a CuB Center into Sperm Whale Myoglobin"
Journal of the American Chemical Society 122, 8192-8196 (2000) [PDF] [doi]
28 | Jing Li, Wenchao Zheng, Angela H. Kwon, Yi Lu
"In vitro selection and characterization of a highly efficient Zn(II)-dependent RNA-cleaving deoxyribozyme"
Nucl. Acids Res. 28, 481-488 (2000) [PDF] [doi]
27 | Steven M. Berry, Xiaotang Wang, Yi Lu
"Ligand replacement study at the His120 site of purple CuA azurin"
Journal of Inorganic Biochemistry 78, 89 - 95 (2000) [PDF] [doi]
1999
26 | Lynette Cunningham, Jing Li, Yi Lu
"Looking for the Needles in a Haystack: Spectroscopic Characterization of Catalytic Metal Binding Site in Nucleic Acid Enzymes"
in "Symposium on RNA Biology III. RNA, Tool and Target", Nucleic acids symposium series, pp. 70-72 (1999)
25 | Jeffrey A. Sigman, Brian C. Kwok, Alan Gengenbach, Yi Lu
"Design and Creation of a Cu(II)-Binding Site in Cytochrome c Peroxidase that Mimics the CuB-heme Center in Terminal Oxidases"
Journal of the American Chemical Society 121, 8949-8950 (1999) [doi]
24 | Alan Gengenbach, Sung Syn, Xiaotang Wang, Yi Lu
"Redesign of Cytochrome c Peroxidase into a Manganese Peroxidase: Role of Tryptophans in Peroxidase Activity"
Biochemistry 38, 11425-11432 (1999) [PDF] [doi]
23 | Jeffrey A. Sigman, Alycen E. Pond, John H. Dawson, Yi Lu
"Engineering Cytochrome c Peroxidase into Cytochrome P450: A Proximal Effect on Heme-Thiolate Ligation"
Biochemistry 38, 11122-11129 (1999) [PDF] [doi]
22 | Xiaotang Wang, Steven M. Berry, Yaomin Xia, Yi Lu
"The Role of Histidine Ligands in the Structure of Purple CuA Azurin"
Journal of the American Chemical Society 121, 7449-7450 (1999) [PDF] [doi]
20 | Xiaotang Wang, Marjorie C. Ang, Yi Lu
"Kinetics of Copper Incorporation into an Engineered Purple Azurin"
Journal of the American Chemical Society 121, 2947-2948 (1999) [PDF] [doi]
19 | Howard Robinson, Marjorie C. Ang, Yi-Gui Gao, Michael T. Hay, Yi Lu, Andrew H.-J. Wang
"Structural Basis of Electron Transfer Modulation in the Purple CuA Center"
Biochemistry 38, 5677-5683 (1999) [PDF] [doi]
18 | Ole Farver, Yi Lu, Majorie C. Ang, Israel Pecht
"Enhanced rate of intramolecular electron transfer in an engineered purple CuA azurin"
Proceedings of the National Academy of Sciences of the United States of America 96, 899-902 (1999) [PDF] [doi]
17 | Tu H. Nguyen, Lynette A. Cunningham, Kendra M. Hammond, Yi Lu
"High-Resolution Preparative-Scale Purification of RNA Using the Prep Cell"
Analytical Biochemistry 269, 216 - 218 (1999) [PDF] [doi]
1998
16 | Lynette A. Cunningham, Jing Li, Yi Lu
"Spectroscopic Evidence for Inner-Sphere Coordination of Metal Ions to the Active Site of a Hammerhead Ribozyme"
Journal of the American Chemical Society 120, 4518-4519 (1998) [PDF] [doi]
15 | Daniel R. Gamelin, David W. Randall, Michael T. Hay, Robert P. Houser, Ton C. Mulder, Gerard W. Canters, Simon de Vries, William B. Tolman, Yi Lu, Edward I. Solomon
"Spectroscopy of Mixed-Valence CuA-Type Centers: Ligand-Field Control of Ground-State Properties Related to Electron Transfer"
Journal of the American Chemical Society 120, 5246-5263 (1998) [PDF] [doi]
14 | Blackburn N. J., Ralle M., Sanders D., Fee J. A., de Vries S., Houser R. P., Tolman W. B., Hay M. T., Lu Y.
"XAS Studies on the CuA Centers of Heme-Copper Oxidases and Loop-Directed Mutants of Azurin: Implications for Redox Reactivity"
in "Spectroscopic Methods in Bioinorganic Chemistry", ACS Symposium Series, Vol. 692, Edward I. Solomon, Keith O. Hodgson, eds.; ACS: Washington, D.C.; pp. 241-259 (1998) [PDF] [doi]
13 | Michael T. Hay, Marjorie C. Ang, Daniel R. Gamelin, Edward I. Solomon, William E. Antholine, Martina Ralle, Ninian J. Blackburn, Priscilla D. Massey, Xiaotang Wang, Angela H. Kwon, Yi Lu
"Spectroscopic Characterization of an Engineered Purple CuA Center in Azurin"
Inorganic Chemistry 37, 191-198 (1998) [PDF] [doi]
1997
12 | Yi Lu, Joan S Valentine
"Engineering metal-binding sites in proteins"
Current Opinion in Structural Biology 7, 495 - 500 (1997) [doi]
11 | Bryan K.S. Yeung, Xiaotang Wang, Jeffrey A. Sigman, Peter A. Petillo, Yi Lu
"Construction and characterization of a manganese-binding site in cytochrome c peroxidase: towards a novel manganese peroxidase"
Chemistry & Biology 4, 215-221 (1997) [PDF] [doi]
1996
10 | Lynette Cunningham, Kirk Kittikamron, Yi Lu
"Preparative-Scale Purification of RNA Using an Efficient Method Which Combines Gel Electrophoresis and Column Chromatography"
Nucl. Acids Res. 24, 3647-3648 (1996) [PDF] [doi]
9 | Michael T. Hay, Richard M. Milberg, Yi Lu
"Preparation and Characterization of Mercury and Silver Derivatives of an Engineered Purple Copper Center in Azurin"
Journal of the American Chemical Society 118, 11976-11977 (1996) [PDF] [doi]
8 | M Hay, J H Richards, Y Lu
"Construction and characterization of an azurin analog for the purple copper site in cytochrome c oxidase"
Proceedings of the National Academy of Sciences of the United States of America 93, 461-464 (1996) [PDF]
1995
7 | Colin R. Andrew, Pekka Lappalainen, Matti Saraste, Michael T. Hay, Yi Lu, Christopher Dennison, Gerard W. Canters, James A. Fee, Nobuhumi Nakamura, Joann Sanders-Loehr
"Engineered Cupredoxins and Bacterial Cytochrome c Oxidases Have Similar CuA Sites: Evidence from Resonance Raman Spectroscopy"
Journal of the American Chemical Society 117, 10759-10760 (1995) [PDF] [doi]
Postdoctoral Work
6 | Y Lu, D R Casimiro, K L Bren, J H Richards, H B Gray
"Structurally engineered cytochromes with unusual ligand-binding properties: expression of Saccharomyces cerevisiae Met-80-->Ala iso-1-cytochrome c"
Proceedings of the National Academy of Sciences of the United States of America 90, 11456-11459 (1993) [PDF]
Graduate Work
5 | Yi Lu, James A. Roe, Christopher J. Bender, Jack Peisach, Lucia Banci, Ivano Bertini, Edith B. Gralla, Joan Selverstone Valentine
"New Type 2 Copper-Cysteinate Proteins. Copper Site Histidine-to-Cysteine Mutants of Yeast Copper-Zinc Superoxide Dismutase"
Inorganic Chemistry 35, 1692-1700 (1996) [PDF] [doi]
4 | Yi Lu, Louis B. LaCroix, Michael D. Lowery, Edward I. Solomon, Christopher J. Bender, Jack Peisach, James A. Roe, Edith B. Gralla, Joan Selverstone Valentine
"Construction of a blue copper site at the native zinc site of yeast copper-zinc superoxide dismutase"
Journal of the American Chemical Society 115, 5907-5918 (1993) [PDF] [doi]
3 | Yi Lu, James A. Roe, Edith G. Gralla, Joan Selverstone Valentine
"Metalloprotein Ligand Redesign: Characterization of Copper-Cysteinate Proteins Derived from Yeast Copper-Zinc Superoxide Dismutase"
in "Bioinorganic Chemistry of Copper", Kenneth D. Karlin, Zoltan Tyeklar, eds.; Chapman & Hall: New York; pp. 64-77 (1993) [doi]
2 | Jane Han, Thomas M. Loehr, Yi Lu, Joan Selverstone Valentine, Bruce A. Averill, Joann Sanders-Loehr
"Resonance Raman excitation profiles indicate multiple Cys -> Cu charge transfer transitions in type 1 copper proteins"
Journal of the American Chemical Society 115, 4256-4263 (1993) [PDF] [doi]
1 | Yi Lu, Edith B. Gralla, James A. Roe, Joan Selverstone Valentine
"The redesign of a type 2 into a type 1 copper protein: construction and characterization of yeast copper, zinc superoxide dismutase mutants"
Journal of the American Chemical Society 114, 3560-3562 (1992) [PDF] [doi]