Dr. Lu’s research interests lie at the interface between chemistry and biology. Specific areas of current interests include a) Computational design and directed evolution of artificial metalloenzymes as environmentally benign biocatalysts for renewable energy generation and pharmaceutical drug syntheses; b) Engineer biocatalysts to address challenges in synthetic organic chemistry and applications of novel biocatalysts in synthetic biology for biomass conversion and valuable products generation; c) Design and selection of sensors and imaging agents for metal ions, metabolites and glycoRNAs to advance metallomics, metabolomics and glycomics for medical diagnosis, imaging and therapy in neurodegenerative and infectious diseases and cancers; d) Using DNA for encoded synthesis and directed assembly of nanomaterials, as well as the applications of these nanomaterials as theranostic agents for early detection of diseases such as cancers and targeted drug delivery; and e) Developing novel gene-editing methods to improve sequence fidelity and gene target accessibility.
Dr. Lu has received numerous research and teaching awards, including the Howard Hughes Medical Institute Professors Award (2002), Fellow of American Association for the Advancement of Science (2007), Fellow of the Royal Society of Chemistry (2015), Royal Society of Chemistry Applied Inorganic Chemistry Award (2015), Joseph Chatt Award (2020) and Fellow of the National Academy of Inventors (2021) and Allen Distinguished Investigators (2022).
Department of Chemistry
University of Texas at Austin
Austin, TX 78712
Phone: (512) 471-1542
Email: yi.lu@utexas.edu
CV
Department of Chemistry
HHMI Professor
Interdisciplinary Life Sciences Graduate Program at UT
John Ring LaMontagne Center for Infectious Disease (CID)
Livestrong Cancer Institutes at the UT Dell Medical School
McKetta Department of Chemical Engineering
Texas Materials Institute
Department of Biomedical Engineering
Institute for Neuroscience